Digestiv Flashcards

1
Q

Ce este achalazia

A

= tulb a MOTILITATII esofagiene caracterizata printr-o RELAXARE INCOMPLETA a SEI in timpul deglutitiei, asociata cu un tonus crescut al SEI IN REPAUS SI IN LIPSA PERISTALTISMULUI ESOFAGIAN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Clasificare achalazie

A
  1. Primara - idiopatica
  2. Secundara: BOALA CHAGAS, DZ, tu maligne, poliomielita, sarcoidoza, amiloidoza
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Achalazie patogeneza

A

1 Primara
-> absenta congenitala/reducerea nr de cel ggl din plez mienteric esofagian (agresiune mediata de LyT)
-> leziuni degenerative ale nervului vag
-> leziuni ale nucleului dorsal al vaguluu

  1. Secundara
    -> distrugere plex mienteric
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Achalazia complicatii

A
  1. Pneumonie de aspiratie
  2. RGEF, EB
  3. Diverticul
  4. Candidoza esofagiana
  5. Stenoza esofagiana
  6. Ulceratii
  7. !! Cc SCUAMOS!!!
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Achalazie - macro

A
  1. Dilatare progresiva a esofagului deasupra SEI => megaesofag
  2. Grosime variabila a peretelui: normala, redusa sau crescuta (hipertrofia musc circulare)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Achalazie - micro

A

Initial:
Inflamatie plex mienteric
-> LyT citotoxice -> folicului cu centrui germinativi si eozinofile
-> atrofie glandulara

Stadii avansate:
1. Reducere imp/ABSENTA cel ggl in plex
2. Inlocuirea nervi cu colagen
3. Hipertrofie musc
4. Hiperplazie ep scuamos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly