Digestive system infections (part 2) Flashcards

1
Q

how are E. coli outbreaks caused?

A

contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk

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2
Q

contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk

A

cause E. coli outbreaks

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3
Q

why is C. diff resistant to disinfectants?

A

it’s a spore former

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4
Q

name some important characteristics of Clostridium difficile

A
  • G+
  • spore former
  • resistant to disinfectants
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5
Q

primarily occurs in hospitalized patients treated with antibiotics

A

C. diff

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6
Q

digestive infection that grows only when the normal flora is disrupted

A

C. diff

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7
Q

C. diff grows only when WHAT condition is met?

A

normal flora is disrupted

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8
Q

C. diff primarily occurs in what circumstances?

A

hospitalized patients treated with antibiotics

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9
Q

asymptomatic colonization

A

C. diff

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10
Q

diarrhea that progresses from mild to moderate to severe

A

CDI

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11
Q

abdominal pain and distension

A

CDI

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12
Q

digestive infection with fever

A

CDI

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13
Q

pseudomembranous colitis

A

CDI

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14
Q

toxic megacolon

A

CDI

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15
Q

perforated colon which leads to sepsis and death

A

CDI

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16
Q

what makes CDI pathogenesis possible?

17
Q

what cells does CDI target? how does it affect those cells?

A

intestinal epithelial cells by disrupting actin

18
Q

digestive system infection that can progress to colitis

19
Q

name some symptoms of CDI

A

asymptomatic colonization
diarrhea
abdominal pain
fever
pseudomembranous colitis
toxic megacolon
perforated colon
sepsis
death

20
Q

destroys intestinal epithelial cells by disrupting actin

21
Q

how to treat CDI

A

specific antibiotics
fecal transplant

22
Q

treated by fecal transplant

23
Q

treated by specific antibiotics

24
Q

how to prevent CDI?

A

reduce antibiotic use, avoid transmission

25
prevented by reducing antibiotic use
CDI
26
pathogenesis of CDI
pili
27
pathogenesis via pili
CDI, E. coli
28
pathogenesis of shigellosis
cell invasion
29
causative agent of Shigellosis
Shigella species
30
destroy intestinal epithelial cells by causing inflammation
shigellosis
31
dysentery
Shigellosis
32
not killed by stomach acid
Shigellosis
33
low infectious dose
Shigellosis
34
you can give antibiotics but they may be resistant
Shigellosis
35
symptoms/characteristics of shigellosis (3)
dysentery not killed by stomach acid low infectious dose