Digestive system infections (part 2) Flashcards

1
Q

how are E. coli outbreaks caused?

A

contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk

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2
Q

contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk

A

cause E. coli outbreaks

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3
Q

why is C. diff resistant to disinfectants?

A

it’s a spore former

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4
Q

name some important characteristics of Clostridium difficile

A
  • G+
  • spore former
  • resistant to disinfectants
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5
Q

primarily occurs in hospitalized patients treated with antibiotics

A

C. diff

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6
Q

digestive infection that grows only when the normal flora is disrupted

A

C. diff

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7
Q

C. diff grows only when WHAT condition is met?

A

normal flora is disrupted

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8
Q

C. diff primarily occurs in what circumstances?

A

hospitalized patients treated with antibiotics

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9
Q

asymptomatic colonization

A

C. diff

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10
Q

diarrhea that progresses from mild to moderate to severe

A

CDI

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11
Q

abdominal pain and distension

A

CDI

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12
Q

digestive infection with fever

A

CDI

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13
Q

pseudomembranous colitis

A

CDI

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14
Q

toxic megacolon

A

CDI

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15
Q

perforated colon which leads to sepsis and death

A

CDI

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16
Q

what makes CDI pathogenesis possible?

A

AB toxins

17
Q

what cells does CDI target? how does it affect those cells?

A

intestinal epithelial cells by disrupting actin

18
Q

digestive system infection that can progress to colitis

A

CDI

19
Q

name some symptoms of CDI

A

asymptomatic colonization
diarrhea
abdominal pain
fever
pseudomembranous colitis
toxic megacolon
perforated colon
sepsis
death

20
Q

destroys intestinal epithelial cells by disrupting actin

A

CDI

21
Q

how to treat CDI

A

specific antibiotics
fecal transplant

22
Q

treated by fecal transplant

A

CDI

23
Q

treated by specific antibiotics

A

CDI

24
Q

how to prevent CDI?

A

reduce antibiotic use, avoid transmission

25
Q

prevented by reducing antibiotic use

A

CDI

26
Q

pathogenesis of CDI

A

pili

27
Q

pathogenesis via pili

A

CDI, E. coli

28
Q

pathogenesis of shigellosis

A

cell invasion

29
Q

causative agent of Shigellosis

A

Shigella species

30
Q

destroy intestinal epithelial cells by causing inflammation

A

shigellosis

31
Q

dysentery

A

Shigellosis

32
Q

not killed by stomach acid

A

Shigellosis

33
Q

low infectious dose

A

Shigellosis

34
Q

you can give antibiotics but they may be resistant

A

Shigellosis

35
Q

symptoms/characteristics of shigellosis (3)

A

dysentery
not killed by stomach acid
low infectious dose