Digestive system infections (part 2) Flashcards
how are E. coli outbreaks caused?
contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk
contaminated ground beef, bean sprouts, green leafy vegetables, apple juice, unpasteurized milk
cause E. coli outbreaks
why is C. diff resistant to disinfectants?
it’s a spore former
name some important characteristics of Clostridium difficile
- G+
- spore former
- resistant to disinfectants
primarily occurs in hospitalized patients treated with antibiotics
C. diff
digestive infection that grows only when the normal flora is disrupted
C. diff
C. diff grows only when WHAT condition is met?
normal flora is disrupted
C. diff primarily occurs in what circumstances?
hospitalized patients treated with antibiotics
asymptomatic colonization
C. diff
diarrhea that progresses from mild to moderate to severe
CDI
abdominal pain and distension
CDI
digestive infection with fever
CDI
pseudomembranous colitis
CDI
toxic megacolon
CDI
perforated colon which leads to sepsis and death
CDI
what makes CDI pathogenesis possible?
AB toxins
what cells does CDI target? how does it affect those cells?
intestinal epithelial cells by disrupting actin
digestive system infection that can progress to colitis
CDI
name some symptoms of CDI
asymptomatic colonization
diarrhea
abdominal pain
fever
pseudomembranous colitis
toxic megacolon
perforated colon
sepsis
death
destroys intestinal epithelial cells by disrupting actin
CDI
how to treat CDI
specific antibiotics
fecal transplant
treated by fecal transplant
CDI
treated by specific antibiotics
CDI
how to prevent CDI?
reduce antibiotic use, avoid transmission