DILI

Question 1

Type of DILI that results as a backup of bile

Answer 1

cholestatic

Question 2

Type of Dili that results in liver necrosis

Answer 2

hepatocellular

Question 3

In cholestasis, there are markedly elevated levels of ___ and ___

Answer 3

GGT and ALKP

Question 4

acetaminophen, isoniazid, pyrazinamide, rifampcin, and sulfonamides are associated with this DILI

Answer 4

hepatocellular

Question 5

amox-clav, cephalosporins, penicillins, sulfonamides, and terbinafine are associated with this DILI

Answer 5

cholestasis

Question 6

R value >5

Answer 6

hepatocellular

Question 7

R value <2

Answer 7

cholestatic

Question 8

The representative drug of cephalosporin-associated DILI

Answer 8

cefazolin

Question 9

Most common cause of DILI behind acetaminophen

Answer 9

Amoxicillin-clavulanate

Question 10

Macrolide that can cause DILI

Answer 10

azithromycin

Question 11

Antitubercular drug that is most likely associated with DILI

Answer 11

isoniazid

Question 12

It takes an average of ___ days for ALT to increased by 5-fold

Answer 12

100 days

Question 13

Antifungals that are associated with a higher risk of DILI

Answer 13

voriconazole, posaconazole