Malaria & RMSF

Question 1

The most worrisome parasite for malaria is plasmodium _____

Answer 1

falciparum

Question 2

In which stage do people get sick from malaria, liver or blood?

Answer 2

Blood

Question 3

The incubation period for malaria can range from __-30 days

Answer 3

7-30 days

Question 4

P. ___ and P. ____ may be in dormant stages for months and have delayed symptoms by weeks to months

Answer 4

P. ovale and P. vivax

Question 5

What needs to be tested for when being considered for taking primaquine?

Answer 5

glucose-6-phosphate dehydrogenase (G6PD) - levels should be positive if taking primaquine

Question 6

Atovaquone/Proguanil should be taken 1-2 ___ before travel and for ___ days after traveling

Answer 6

1-2 days before travel and for 7 days after traveling

Question 7

Atovaquone/Proguanil is a once daily medication (T/F)

Answer 7

True

Question 8

Which malaria medication should be avoided in pregnancy and severe renal impairment?

Answer 8

Atovaquone/Proguanil

Question 9

Are pediatric tablets available for atovaquone/proguanil?

Answer 9

Yes

Question 10

Chloroquine should be taken 1-2 ____ before traveling and for ____ weeks after traveling

Answer 10

1-2 weeks before traveling and for 4 weeks after traveling

Question 11

Chloroquine is a daily medication (T/F)

Answer 11

False, weekly medication

Question 12

Patients taking ______ chronically may not need to take chloroquine

Answer 12

hydroxycholorquine

Question 13

Chloroquine is good for short trips (T/F)

Answer 13

False, good for long trips due to weekly dose

Question 14

Which malaria medication can exacerbate psoriasis?

Answer 14

Chloroquine

Question 15

What needs to be checked before starting chloroquine?

Answer 15

Chloroquine susceptibility

Question 16

Doxycycline should be taken 1-2 ___ before traveling and for ___ weeks after traveling

Answer 16

1-2 days before traveling and for 4 weeks after traveling

Question 17

Doxycycline is a ___ medication

Answer 17

daily medication

Question 18

Which malaria medication should not be used by pregnant women or children <8 years old?

Answer 18

Doxycycline

Question 19

Which malaria medication causes an increased risk of sun sensitivity?

Answer 19

Doxycycline

Question 20

Which malaria medication can cause an upset stomach and should be swallowed completely with a full glass of water in order to prevent esophageal damage?

Answer 20

Doxycycline

Question 21

Which malaria medication is highly controversial due to its psychiatric side effects?

Answer 21

Mefloquine

Question 22

Mefloquine should be taken 1-2 ___ before traveling and for ___ weeks after traveling

Answer 22

1-2 weeks before traveling and for 4 weeks after traveling

Question 23

Mefloquine is a weekly medicine (T/F)

Answer 23

True

Question 24

Which malaria medications are okay in pregnancy?

Answer 24

Mefloquine and chloroquine

Question 25

Which malaria medications are good for short trips?

Answer 25

atovaquone/proguanil & primaquine

Question 26

Which malaria medications are not good for last minute travelers?

Answer 26

chloroquine, mefloquine

Question 27

___ is commonly used to prevent P. vivax after return from travel

Answer 27

Primaquine

Question 28

Primaquine should be taken 1-2 ___ before traveling, daily during travel, and for ___ days after traveling

Answer 28

1-2 days before traveling, daily during travel, and for 7 days after traveling

Question 29

Primaquine is okay to use in pregnancy (T/F)

Answer 29

False

Question 30

What malaria medicine is preferred in P. falciparum in areas with chloroquine resistance?

Answer 30

Artemether-lumefantrine (Coartem)

Question 31

For severe malaria, IV artesunate is first line (T/F)

Answer 31

True

Question 32

Artemether-lumefantrine (Coartem) or atovaquone-progunail or quinine or mefloquine can be given for severe malaria until the IV artesunate arrives (T/F)

Answer 32

True

Question 33

Rickettsia reckettsii causes Rocky Mountain Spotted Fever (T/F)

Answer 33

True

Question 34

The appearance of a rash is diagnostic for RMSF and a reliable symptom (T/F)

Answer 34

False, rash may/may not appear, can be helpful in diagnosing but not something you can rely on

Question 35

RMSF rash can spread to the trunk and be on the palms and soles of feet (T/F)

Answer 35

True

Question 36

What STI does the RMSF rash remind you of?

Answer 36

Secondary syphilis! (rash appears on body, palms, and soles of feet) but in syphilis, the rash goes away

Question 37

Empiric treatment for RMSF is

Answer 37

Doxycycline

Question 38

RMSF is the only case you do not have to worry about age for giving doxycycline (T/F)

Answer 38

True, can be given in children <8 years because need to treat empirically early