Diseases Affecting the Brain Flashcards
CMRO2 can be decreased by what? increased by?
temperature reductions and various anesthetic agents;
temperature increases and seizures
Autoregulation of CBF is altered in the presence of _____
chronic HTN
_____ is considered a cerebral vasodilator
Ketamine
Potent cerebral vasoconstrictors capable of decreasing CBF, CBV, and ICP
Propofol and barbiturates (thiopental)
CSF is produced at a constant rate of _____ in adults
500-600 ml/day
Where is CSF absorbed?
From microscopic arachnoid vili within the dura mater and bordering venous sinusoids and sinuses
Which drugs/fluids are effective in decreasing ICP?
mannitol & hypertonic saline
Corticosteroids are not effective in reducing ICP in which pts?
closed head injury
_____ should not be administered for nausea and vomiting prophylaxis during pituitary tumor resection
Corticosteroids such as dexamethasone
Why should glucose-containing solutions be avoided?
hyperglycemia in the setting of CNS ischemia will exacerbate neuronal injury and worsen outcome
What will you see first with an air embolism?
A sudden decrease in ETCO2 may reflect increased alveolar dead space and/or diminished cardiac output resulting from air embolism
What is the anesthetic goal for patients diagnosed with brain death undergoing surgery for multi organ retrieval?
To optimize oxygenation and perfusion of the organs to be retrieved
How long should elective surgery be delayed following a stroke?
9 months
The classic triad of major signs of Parkinson’s
skeletal muscle tremor, rigidity, & akinesia
How does increases in body temperature affect multiple sclerosis?
causes exacerbation of symptoms
