diseases in the CNS Flashcards

(33 cards)

1
Q

frontal lobe

A

motor control, speech, smell

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2
Q

parietal lobe

A

touch, taste, body awareness

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3
Q

temporal lobe

A

hearing, facial recognition

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4
Q

occipital lobe

A

vision

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5
Q

cerebellum

A

coordination

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6
Q

neuronal cell body

A

grey matter

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7
Q

neuronal fibres

A

white matter

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8
Q

microglial cell

A

defence and immune support

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9
Q

astrocyte

A

structural and metabolic support, repair

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10
Q

ependymal cell

A

assist in production and movement of cerebral spinal fluid

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11
Q

oligodendrocyte

A

produce myelin and provide electrical insulation

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12
Q

hypoxia/ischemia

A

red neurons

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13
Q

neurodegenerative diseases/viral infections

A

intracellular inclusions, dystrophic neurites

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14
Q

astrocyte injury and repair

A

gliosis, reactive astrocytes causing hypertrophy and hyperplasia

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15
Q

gliosis

A

proliferation and hypertrophy of glial cells in response to injury

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16
Q

cerebral oedema

A

accumulation of excess fluid within the brain parenchyma

17
Q

hydrocephalus

A

increase in fluid volume within ventricular system which increases intracranial pressure

18
Q

herniation

A

displacement of brain tissue from one compartment to another due to increased intracranial pressure

19
Q

stroke

A

caused by poor quality of blood vessels

20
Q

meningitis

A

bacterial infection within the subarachnoid space, causes damage to the CNS

21
Q

meningoencephalitis

A

infection spreads into the underlying brain

22
Q

myelin

A

electrical insulator allowing rapid propragation of impulses

23
Q

demyelinating diseases

A

damage to normal myelin

24
Q

dysmyelinating diseases or leukodystrophy

A

myelin is not properly formed

25
multiple sclerosis
distinct episodes of neurologic deficits, caused by autoimmune response directed against myelin
26
relapsing-remitting MS
attack of new or worsening of syptoms, after attack they disappear
27
progressive-relapsing MS
symptoms will gradually become more severe, distinction between attack and remission
28
secondary progressive MS
symptoms will become more severe, no distinction between attack and remission
29
primary progressive MS
symptoms get gradually worse over time, no attacks but symptoms throughout their lives
30
active plaques
abundant macrophages and t cells
31
inactive plaques
no inflammation but no myelin, gliolisis
32
alzheimer disease
caused by accumulation of Tau proteins and beta-amyloid plaques
33
parkinson
movement disorder caused by loss of dopaminergic neurons in substantia nigra