Disorders Flashcards
sign in plateau iris
sine-wave sign
plateau iris - PAS formation
begins at Schwalbe line and extends posteriorly
ICE syndrome - features, glaucoma more severe in…
vessels cross TM, high PAS extend over Schwalbe line, uni, F 20-50, glaucoma more severe in essential iris atrophy and Cogan Reese
ICE syndrome - cornea
beaten bronze metal
Cogan-Reese syndrome
multiple, pedunculated iris nodules
Chandler syndrome
corneal edema
Essential iris atrophy
corectopia and hole formation
ICE syndrome - which variant is the most common
Chandler syndrome
angle recession - definition
tear in the ciliary body, typically between the longitudinal and circular muscle fibers
angle recession - features in gonioscopy
torn or absent iris processes, “glistening” scleral spur, depression in TM, PAS at the border of recession
Posner-Schlossman - uni or bi, sex, age, virus, features, what if steroids and lowering IOP does not help
uni, M, 20-30 yo, (pylori,HSC), CMV, diffuse iris atrophy, absent PAS, topical 2% ganciclovir, then oral Vanganciclovir
Where notches of optic disc in early glaucoma
inferior and superior temporal
What is NOT effective in CIE syndrome?
Miotics (pilocarpine), SLT
Juvenile glaucoma - gene
GLC1A = TIGR/MYOC (protein myocilin)
3% POAG - gene
GLC1A = TIGR/MYOC (protein myocilin)
Primary congenital glaucoma - gene
CYP1B1 (GLC3A)
Normal tension glaucoma - gene
OPTN, GLC1B
Iridoschisis - definition
separation of the anterior iris stroma from the posterior iris stroma
Signs of elevated episcleral venous pressure (EVP)
“corkscrew vessels”, blood in Schlemm’s canal, proptosis, wide ocular pulse amplitude->pulsations, orbital bruit
Normal tension glaucoma - sings
nerve fiber later hemorrhages (escpecially inferotemporally), peripapillary atrophy, disc notching, disc sloping, larger optic disc size, VF - defects depper and closer to fixation
Essential Iris Atrophy
severe progressive iris atrophy causing heterochromia, corectopia, extropion uveae, iris hole formation. glaucoma severe
Chandler syndrome
minimal iris changes. corneal and angle chamges predominate
Cogan-Reese syndrome
less iris atrophy. tan pedunculated nodules or diffuse pigmented lesions on the anterior iris surface glaucoma severe
Which population has the highest prevalence of primary angle closure glaucoma
Inuits