Disorders of the Immune System

Question 1

You see a baby for recurrent bacterial skin infections requiring antibiotic treatment and incision/drainage. Labs reveal absent CD18 on the surface of leukocytes. What other feature would you expect in this patient?

A. Infection following live-virus vaccines

B. Infection with Neisseria species

C. Persistent leukocytosis

D. Small or absent lymph nodes

E. Thrombocytopenia

Answer 1

C. Persistent leukocytosis

This is leukocyte adhesion deficiency and the fucking leukocytes cant extravasate out of blood vessels -> leukocytosis