Diuretics

Question 1

list different types of diuretic

Answer 1

carbonic anhydrase inhibbitors 
loop 
thiazide 
thiazide like 
potassium psparing

Question 2

example of carbonic anhydrase inhibitors

Answer 2

acetazolamide

Question 3

method of action of carbonic anhydrase inhibbitors

Answer 3

excretion of bicarb

Question 4

indication of carbonic anhydrase inhibbitors

Answer 4

glaucoma

mountain sickness

Question 5

example of loop diuretic

Answer 5

furosemide

Question 6

MoA loop diuretic

Answer 6

inhibits Na/K/2Cl transporter > inhibits reabsorption of these ions
> water dragged out

Question 7

SE of loop diuretics

Answer 7

low sodium, low potassium > alkalosis

raised urate. raised glucose

Question 8

example of thiazide

Answer 8

bendroflumethazide

Question 9

MoA thiazide

Answer 9

inhhibit Na/Cl channel > inhibits Na reabsorption

Question 10

SE thiazide

Answer 10

low K+ (as K+ is excreted to try and drag Na back in)
met alkalosis
high calcium

Question 11

example of TLD

Answer 11

indapamide

Question 12

example of potassium sparing drugs

Answer 12

spironolactone (aldosterone antagonist)

Question 13

SE spironolactone

Answer 13

high K+

gynaecomastia (weakly binds to androgen receptor)