DM Flashcards

(32 cards)

1
Q

Hormone that Increases in DM

A

Glucagon
Epinephrine
Cortisol
hGH

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2
Q

Type of DM characterized by being Autoimmune
–Selective destruction of βcells by lymphocytes
– Circulation antibodies

A

Type 1

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3
Q

Viral risks factors for DM1

A

Coxsackie
Pox Virus
Rubella

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4
Q

Nutrimental risk factors for DM1

A

Cow Milk

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5
Q

DM2 can be both by ____ or ____

A
Insulin action deficiency 
Insulin deficiency (Beta cell destruction)
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6
Q

In. DM2, insulin action deficiency produces _____ production by the liver and _____ glucosee utilization by muscle or adipocytes

A

More glucose

Less

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7
Q

a lot of glucose in the blood produces glucose ____

A

Secretion in urine

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8
Q

As there is no glucose uptake, cells such as miocytes or adipocytes, go to the ___ pathway, and then ____

A

proteolisis/lipolisis

Gluconeogénesis

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9
Q

Familiar background is related in DM type ___

A

DM2

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10
Q

Obesity is not common in DM type ___

A

DM1

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11
Q

3 pls in diabetes stand for ___

A

Polydipsia, Polyfagi, polyuria

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12
Q

Acute complications od DM

A

Hypoglicemia, Ketoacidosis, Non Keto hyperosmolar staate

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13
Q

Chronic complications of DM divide into

A

Macrovascular

Microvascular

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14
Q

Crónica macrovascular complications of DM

A

Coronary disease
Cardiovascular disease
Periphereal vascular disease

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15
Q

crónica microvascular complications of DM

A

Retinopathy
Neuropathy
Nefropathy

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16
Q

Diabetic level of glucose while fasting

17
Q

Diabetic level of glucose postprandial

18
Q

Diabetic HbA1C levels

A

> 6.5 mg(dl

(5.6 sano)

19
Q

Sulfonylureas such as Glibenclamide is not indicated in Px with

A

Kidney Failure

20
Q

Biguanids such as Metformin is not indicated in

A

Kidney or liver failure, alcoholismo, lactic acidosis

21
Q

They produce insulin secretion by K channel, but you gain weight and may produce hypoglicemia

A

Sulfonylureas

22
Q

Produces decreased hepatic production of glucose and increases muscle sensitivity to it, as lowering GI glucose absorption

23
Q

Metformin side effect is

24
Q

It binds to peroxisome proliferative protein increasing insulin sensitivity in liver and muscle

A

Thiazolidinediones

25
They inhibit brush border enzymes but can cause diarreah, flatulence
A-glucosiddase inhibidos
26
Increase incretine levels which disminishes glucagon release and increases insulin realease Diminishes gastric emptying
May produce headache DPP-4
27
may produce pancreatitis, vomito an diarrhea • Disminish gastric emptying Increase insulin release Supress glucagon secretion
glp-1 aGONISTAAS
28
block glucose reabsorption from kidneys, increases urine secretion of it
Inh SGLT-2
29
iN THERAPY, the glucose goal for the diabetic is ___ while fasting, ___ after meal and ___ HbA1C
0 | 80-110; <140; <7%
30
The non vascular chronic complications for DM
Gastroparesis Sexual dysfunction Skin dehydration
31
These are complications of DM called____ • • • Burning pain in both feet (socks) and hands (gloves) Paresthesias, disesthesias Fine stinging paresthesias, electrical paroxisms Allodynia to mechanical touch and thermal heat
Neuropathy
32
Pie diabético in inglich
Charcot foot