DNA and Chromosomal Mutations

Question 1

Define mutation and mutagenesis

Answer 1

H

Question 2

Explian and describe the consequences of single nucleotide (and other small) mutations

Answer 2

D

Question 3

Define and describe the consquences of missense, nonsense, farmeshift, silent/neutral, synonymous and non-synonymous mutations, as well as mutations of the stop codon and regulatory sequences

Answer 3

P

Question 4

Explain how fork slippage and transposable ellements cause mutations

Answer 4

P

Question 5

Describe in general terms the potential conseqeunces of mutations at the gene level

Answer 5

K

Question 6

Define and describe numerical and structural chromosomal abnormalities

Answer 6

A

Question 7

Explain and describe in general terms the consequences of chromosomal mutations

Answer 7

J

Question 8

Define trisomy and monosomy, and describe examples of known syndromes associated with these

Answer 8

G

Question 9

Describe reciprocal and Robertsonian translocations and their potential consequences in both somatic and germ line cells

Answer 9

F

Question 10

Describe and appreciate cytogenetic testing

Answer 10

G