DNA replication Flashcards

1
Q

Semiconservative replication

A

a mechanism of DNA replication, each of the two strands of parent DNA is incorporated into new double-stranded DNA molecule

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2
Q

replication origin

A

specific sequence of DNA, acts as starting point for replication

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3
Q

helicase

A

replication enzyme, separates and unwinds DNA helix

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4
Q

replication fork

A

point of separation of two parent DNA strands during replication

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5
Q

topoisomerases

A

class of enzymes that relieve tension caused by unwinding of parent DNA

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6
Q

single-strand binding protein

A

replication enzyme that prevents parent DNA strands from annealing to eachother

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7
Q

replication bubble

A

seperating of DNA in both directions during replication

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8
Q

nucleoside triphosphate

A

building block and energy source for replicating DNA

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9
Q

RNA primase

A

replication enzyme that produces RNA primers on template strands

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10
Q

RNA primer

A

replication molecule that acts as a starting point for replication

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11
Q

DNA polymerase III

A

prokaryotic replication enzyme that build new DNA strands from nucleotides

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12
Q

leading strand

A

DNA strand that is copied in direction towards replication fork

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13
Q

lagging strand

A

DNA strand copied in direction away from replication fork

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14
Q

Okazaki fragment

A

piece of new DNA on the lagging strand

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15
Q

DNA polymerase I

A

prokaryotic replication enzyme that fills in gaps in the lagging strand between Okazaki fragments

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16
Q

DNA ligase

A

enzyme that catalyzes formation of a phosphodiester bond between two DNA strands and Okazaki fragments

17
Q

DNA polymerase II

A

prokaryotic replication enzyme that repairs damage to DNA

18
Q

Cell senescence

A

period in a cell’s lifespan when it loses ability to divide and grow, referred to as cell aging

19
Q

Hayflick limit

A

total number of times that a normal cell van divide

20
Q

telomerase

A

enzyme that adds new telomere sequences to the ends of chromosomes