DNA + RNA Flashcards

(54 cards)

1
Q

Dna molecules contains

A

Genes

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2
Q

A gene is a segment of DNA that makes instructions for making

A

Protein/polypeptide

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3
Q

An allele are

A

Two versions of a gene

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4
Q

A cell needs many different types of proteins to function
Enzymes
Transport proteins

A

Enzymes carry out chemical reactions to sustain life

Transport proteins move ions and molecules across the cell membrane

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5
Q

Genes influence an organism’s characteristics by determining the

A

protein made

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6
Q

Early in the 1900s, people didn’t know if the basis for molecules was

A

Protein or dna

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7
Q

Frederick Griffith

A

killed pathogens and mixed harmless bacteria with their corpses, and some of the bacteria became pathogens

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8
Q

Hershey and Chase

A

found that viruses inject their DNA into cells to reproduce (nucleotides??)

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9
Q

Nucleotides are

A

Nitrogenous base
Five-carbon sugar (deoxyribose)
Phosphate group

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10
Q

Nucleotides are joined together by a

A

sugar-phosphate backbone

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11
Q

There are four nitrogen-containing bases

A

Adenine (A)
Cytosine (C)
Thymine (T)
Guanine (G)

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12
Q

DNA and RNA are

A

polymers of nucleotides

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13
Q

Purines have a double ring structure

A

Adenine, Guanine

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14
Q

Pyrimidines have a single ring structure

A

Cytosine, Uracil, Thymine

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15
Q

DNA abbrev

A

deoxyribonucleic acid

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16
Q

RNA abbrev

A

ribonucleic acid

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17
Q

RNA

A

Ribose
Uracil (U)
Single stranded
Copies genetic code for protein

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18
Q

DNA

A

Deoxyribose
Thymine (T)
Double stranded
Is genetic code for protein

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19
Q

Watson and Crick were the first to figure out the structure of DNA

A

two polynucleotide strands wrapped around each other in a double helix

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20
Q

Hydrogen bonds

A

holds the strands together

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21
Q

Each base has a complementary partner

A

Adenine and Thymine
Guanine and Cytosine

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22
Q

The genetic information in a chromosome is enclosed in

A

the nucleotide sequence in DNA

23
Q

Enzymes use the stands to make new nucleotides

24
Q

DNA replication follows a semiconservative model

A

one old strand of DNA and one new strand

25
Meselson and Stahl researched
Dna replication
26
Steps of dna replication
Helicase splits DNA strands into two different pieces Primase makes RNA strands called primers DNA polymerase binds to the primer and make new DNA DNA polymerase can only make DNA in one direction (5 prime to 3 prime), which is called the leading strand The other strand, called the lagging strand, has to be filled in with fragments, called Okazaki fragments DNA ligase binds the Okazaki fragments Exonuclease removes the RNA primers and is filled in with DNA
27
DNA polymerase can only add to the 3 prime end because it has a
hydroxyl for dehydration reaction
28
Leading strand Lagging strand
5' to 3' 3' to 5'
29
Transcription process
Hydrogen bonds between the bases of the DNA helix are broken by DNA helicase RNA nucleotides line up and RNA polymerase joins them along one strand of DNA The promoter signals the start and acts as a binding site for RNA polymerase RNA polymerase adds RNA nucleotides until it reaches the terminator, which signals the end of the gene
30
RNA that encodes amino acid sequence is called
messenger RNA (mRNA) because it tells genetic messages from DNA to the translation machinery of the cell
31
Before leaving the nucleus as mRNA
eukaryotic transcripts undergo RNA splicing:
32
RNA splicing
Introns (non-coding segments of RNA) are spliced out Exons (coding segments of RNA) are spliced together, and a 5’ cap and a poly A tail are added to the ends of the mRNA
33
The sequence of nucleotides in DNA provides a code for
Constructing a protein
34
Translation requires nucleotide sequence to turn to
amino acid sequence
35
DNA->Transcription->mRNA->Translation->Polypeptide
Got it?
36
The genetic instructions for the amino acid sequence is written in DNA and RNA called
Codon
37
Codons are a series of
nonoverlapping three-base “words”
38
The genetic code is a set of rules that translates mRNA to
amino acids/polypeptides
39
Ribosomes attach to mRNA and translates the message to polypeptides, aided by
transfer RNAs (tRNA)
40
tRNA is a folded molecule with a base triplet called.. on one end and an.. on the other
Anticodons ; amino acid attachment site
41
Ribosomes are made of
ribosomal RNA (rRNA) and proteins
42
Ribosomes have binding sites for
tRNA and mRNA
43
Translation has three phases
Initiation Elongation Termination
44
Initiation
An mRNA, a tRNA with methionine, and two subunits of a ribosome meet The initiator tRNA binds them all to the P site, where the start codon AUG is located
45
Elongation+Termination
As the mRNA moves the codons, a tRNA with a complementary anticodon pairs with the codons, adding its amino acids to the polypeptide chain The tRNA is then translocated from the P site to the E site Elongation continues until a stop codon reaches the A site and calls for termination
46
Mutations are changes in the .. for....
Genetic material ; cells or viruses
47
Point mutations are ... in ...
Chemical changes ; one nucleotide pair of genes
48
A change in a single nucleotide can cause
abnormal proteins
49
If a point mutation occurs in a gamete (reproductive cell), it may be transmitted to
To offspring
50
Point mutation
Single nucleotide-pair substitution Nucleotide-pair insertion or deletion
51
Nucleotide-pair substitution
Replaces one pair of nucleotide and its partner with another pair
52
Silent mutation
The codons change, but they still code for the same amino acid, making it redundant
53
Missense mutation
The codons still code for an amino acid, just not the right one Substitution mutations are usually missense mutations
54