DNA Structure Flashcards
(12 cards)
Erwin Chargaff did…
the amount of adenine (A) equals thymine (T) and the amount of cytosine (C) equals guanine (G)
Gregor Mendel did…
Established the foundational principles of genetics (dominance, segregation)
Rosalind Franklin did…
Took X-ray images of DNA, providing crucial data that helped determine the double-helix structure of DNA.
Maurice Wilkins did…
Worked with Franklin on the X-ray diffraction images of DNA and shared crucial data with Watson and Crick, which contributed to the discovery of the DNA double helix.
Watson and Crick did…
Co-discovered the structure of DNA (double-helix)
Components of a DNA nucleotide
1) Phosphate group
2) Deoxyribose sugar
3) Nitrogenous base
Base pairing
A=T
C=G
Anti-parallel definition
The two strands of DNA run in opposite directions. (One strand has a 5’ to 3’ direction, and the other 3’ to 5’ direction.)
Why anti-parallel is important…
The antiparallel structure allows both strands of DNA to be copied at the same time but in opposite directions.
Leading strand
Synthesized continuously in the 5’ to 3’ direction, moving toward the replication
Lagging strand
Synthesized discontinuously in fragments, as DNA polymerase works in the opposite direction of the replication fork, and then the fragments are joined together later.
Double Helix shape
Completes one full turn every 10 base pairs