DNA VIRUS - PAPOVIRIDAE

Question 1

The 2nd SMALLEST DNA VIRUS

Answer 1

Papoviridae

Question 2

Infect SQUAMOUS CELLS and induce formation of CYTOPLASMIC VACUOLE (KOILOCYTES)

Answer 2

Human Papillomavirus

Question 3

Encode proteins that INACTIVATE TUMOR SUPPRESSOR GENES

Answer 3

E6 - (-) p53

E7 - (-) Rb

Question 4

Promote VIRAL DNA REPLICATION

Answer 4

Genes E1 and E2

Question 5

Skin and plantar warts, verruca vulgaris

Answer 5

HPV 1,2,4,7

Question 6

MC VIRAL STD
genital warts (CONDYLOMA ACUMINATA)
respiratory tract papillomas

Answer 6

HPV 6 and 11

Question 7

Carcinoma of the cervix, vulva, penis and anus

Answer 7

HPV 16, 18, 31, 33

Question 8

Only causes disease in IMMUNOCOMPROMISED hosts

Causes of PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY in patients with AIDS

Answer 8

JC Polyoma Virus

Question 9

DEMYELINATING DISEASE that affects the OLIGODENDROCYTES characterized by deficits in SPEECH, COORDINATION and MEMORY

Answer 9

Progressive Multifocal Encephalopathy

Question 10

Causes disease in IMMUNOCOMPROMISED hosts

HEMORRHAGIC CYSTITIS and NEPHROPATHY in patients with solid organ (KIDNEY) and BM transplants

Answer 10

BK Polyoma Virus