1. Photo ID 2. Check date of last donation 3. Deferral status checked 4. Consent to donate - signed form

- the donation process - infectious disease transmission via transfusion - circumstances when testing isn't done

- Female Hgb > 12.5 g/dl for females - Male Hgb > 13.0 g/dl

Donor selection Flashcards by MC GC

Blood inventory management

Volunteer donors (40% US population eligible, but <10% actually donate)

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List process of donating blood

Donor selection: registration, ID donor, donor education
Eligibility: questionnaire, mini-health physical
Collection: phlebotomy and post-donation care

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Acceptable types of ID

donor card
driver’s license
passport
school ID (must be age > 16)

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How long do you have to wait to donate if you donated whole blood?

56 days

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How long do you have to wait to donate if you donated double RBCs?

112 days
up to 3x a year

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How long do you have to wait to donate if you donated platelets?

7 days according to Red Cross
2 days according to FDA
up to 24x a year

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How long do you have to wait to donate if you donated plasma?

28 days
up to 13x a year

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Steps of donor ID

Photo ID
Check date of last donation
Deferral status checked
Consent to donate - signed form

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Donor education

the donation process
infectious disease transmission via transfusion
circumstances when testing isn’t done

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Why may infectious disease testing not be done?

tests available but may not detect early-stage or window-period infection
tests available but not universally used by donor centers
no licensed tests available for donor screening

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No licensed tests available for donor screening for which diseases?

babesiosis
CJD
malaria

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Mini-physical: general appearance

Skin free of scars and needle marks
Eyes clear, no pupil dilation, no yellow sclera

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Mini-physical: H/H

Female Hgb > 12.5 g/dl for females
Male Hgb > 13.0 g/dl

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Mini-physical temp

No greater than 37.5 C or 99.5 F

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BP and pulse criteria

BP<180/100
pulse 50-100 bpm

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Weight

Weight > 110 pounds

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Which infectious agents are ruled out by questioning only?

malaria
prions
Ebola

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Which infectious agents are ruled out by donor testing only?

WNV
Chagas

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Which infectious agents are ruled out by both questioning and testing?

HIV
HBV
HCV
Zika
Babesia
Syphilis

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Which infectious agent must test negative for specific recipients?

CMV

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Blood collection must not exceed ____, otherwise

15 min
throw away bag if exceed 15 min

List donor possible adverse reactions

Vasovagal reaction (fainting)
Hyperventilation
Hypotensive shock
Hematoma
Twitching/muscle spasms
Cardiac difficulties

How to treat vasophagal reaction?

Stop phlebotomy
Elevate legs above head
Cold compress forehead and neck
Aromatic spirits

For donation from relative
Lower risk of:
Higher risk of:

Lower risk of alloimmunization
Higher risk of disease transmission, graft vs host disease

Autologous donation associated with higher risk of ___

Transfusion associated circulatory overload (given more blood than needed) (TACO)

How to handle accepted donor who weighs < 110 lbs

Calculate anticoag amount for low volume

Deferral time for potential bacterial contamination or donor health

Today

Deferral time for aspirin for platelets

48 hrs

Deferral time for vaccines (LAV) or antibiotics

2 wks

Deferral time for pregnancy

6 wk

Deferral time for past donation

8 wks* depends on type of donation

Deferral time for risky behavior, treated STD, transfusion

3 months

Deferral time for incarceration

12 mth

Deferral time for positive Babesia NAT test

2 yr

Deferral time for malaria infection or living in malaria-endemic location

3 yr

Deferral time for: - positive Hep or HIV test - CJD risk - bleeding condition - heart or lung condition

permanent/indefinite

Why test for ABO and Rh in donor testing?

Detect weak subgroups and weak D

List required infectious disease testing and deferral categories

- **permanent**: HBV/HCV, HIV - **temporary**: WNV, syphilis, Babesia - **indefinite**: T.cruzi Ab

Syphilis testing

1. Screen w RPR and hemagglutination 2. Confirm with FTA-ABS or other FDA-approved EIA test

How to decrease treponemal risk of transmission?

Cold storage bc treponemes are fragile and sensitive to cold

Syphilis deferral time

12 mth post-treatment

HCV deferral

permanent

HTLV deferral

permanent/indefinite

WNV deferral

120 days

Zika deferral

4 wks

COVID-19 deferral

14 days for symptoms or pos antigen test *blood donations not tested for COVID-19* *no deferral for vaccine or pos antibody test*

LAV deferral

2-4 wk

Synthetic vaccine deferral

none

List medications that get you deferred

- Abx - GH - HepBIG - Plavix - Accutane - Tegison - Aspirin

**Which virus is not detected through NAT?** HCV HBV HTLV WNV

HTLV bc no risk