Dose Constraints

Question 1

In NB, what dose constraint is used for the contralat kidney per COG ANBL0532?

Answer 1

Limit the dose to V12 <20%, V8 <50%.

Question 2

In NB, what dose constraint is used for the liver per COG ANBL0532?

Answer 2

Limit liver V9 <50%, V18 <25%.

Question 3

In NB, what dose constraint is used for the lung per COG ANBL0532?

Answer 3

Limit lung V15 to <33%.

Question 4

What are some complications of RT Tx in NB?

Answer 4

Disturbances of growth, infertility, neuropsychologic sequelae, endocrinopathies, cardiac effects, pulmonary effects, bladder dysfunction, secondary malignancy