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Pharmacology > Doses, DOA, Onset... > Flashcards

Doses, DOA, Onset... Flashcards

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1
Q

Succinylcholine onset

A

30-60s

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2
Q

Succinylcholine DOA

A

5-10min

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3
Q

Succinylcholine ED95

A

0.25-0.5 mg/kg

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4
Q

Succinylcholine Intubating

A

1-1.5mg/kg (1.5mg/kg for rapid sequence)

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5
Q

Pancuronium Bromide ED95

A

0.07mg/kg

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6
Q

Pancuronium Bromide Intubating Dose

A

0.1 mg/kg

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7
Q

Pancuronium Bromide Onset

A

3-5 min (slow)

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8
Q

Pancuronium Bromide DOA

A

60-90 min (long)

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9
Q

Doxacurium (Benzylisoquinolinium) ED95

A

0.03 mg/kg

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10
Q

Doxacurium (Benzylisoquinolinium) Onset

A

4-6 min

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11
Q

Doxacurium (Benzylisoquinolinium) DOA

A

60-90 min

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12
Q

Pipercuronium (Bisquaternary aminosteroid) ED 95

A

0.055 mg/kg

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13
Q

Pipercuronium (Bisquaternary aminosteroid) Onset

A

3-5 min

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14
Q

Pipercuronium (Bisquaternary aminosteroid) DOA

A

60-90 min

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15
Q

Vercuronium Bromide ED95

A

0.05 mg/kg

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16
Q

Vercuronium Bromide (intubating dose)

A

0.1 mg/kg

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17
Q

Vercuronium Bromide onset

A

3-5 min

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18
Q

Vercuronium Bromide DOA

A

20-35 min

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19
Q

Rocuronium Bromide ED95

A

0.3 mg/kg

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20
Q

Rocuronium Bromide (induction dose)

A

0.6 mg/kg (rapid: 1.2 mg/kg)

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21
Q

Rocuronium Bromide onset

A

1-2 min (rapid: 30-45 sec)

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22
Q

Rocuronium Bromide DOA

A

20-35 min (rapid: 60-90 min)

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23
Q

Atracurium Bromide ED95

A

0.2 mg/kg

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24
Q

Atracurium Bromide (intubating dose)

A

0.5 mg/kg

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25
Atracurium Bromide onset
3-5 min
26
Atracurium Bromide DOA
20-35 min
27
Cistracurium Bromide ED95
0.05 mg/kg
28
Cistracurium Bromide (intubating dose)
0.2 mg/kg
29
Cistracurium Bromide onset
3-5 min
30
Cistracurium Bromide DOA
20-35 min
31
Mivacurium ED95
0.08 mg/kg
32
Mivacurium (intubating dose)
0.25 mg/kg
33
Mivacurium onset
2-3 min
34
Mivacurium DOA
12-20 min
35
Midazolam (induction)
0.1-0.3 mg/kg
36
% solution
g/100ml
37
Methohexital Induction
- 1-1.5 mg/kg - peds: 1-2mg/kg - peds rectal: 20-30 mg PR
38
Lorazapam
50 mcg/kg (up to 4 mg)
39
Propofol (induction)
- 1.5-2.5 mg/kg IV - peds: 2-3 mg/kg IV - elderly 25-50% dose reduction
40
Propofol (maintenance dosing)
- 100-300 mcg/kg/min - peds book 60-250 mcg/kg/min - peds reeality 200-400 mcg/kg/min
41
Propofol (IV sedation)
25-100 mcg/kg/min | 2 mg/kg/hr for amnesia unstimulated =33mcg/kg/min
42
Propofol PONV
10-15mg PACU
43
Propofol (anti-epilectic)
2 mg/kg bolus
44
Etomidate (induction)
0.2-0.4 mg/kg
45
Ketamine (induction)
- 1-2 mg/kg IV bolus | - 4-8 mg/kg IM
46
Sodium Thiopentol Induction
- 3-5 mg/kg IV (decrease 18% pregnancy) | - 5-6 mg/kg IV peds
47
Methylnatrexone
0.3 mg/kg
48
Nalmefene
0.2-2 mg/kg
49
Natrexone
0.2-2 mg/kg
50
Naloxone
1-4 mcg/kg DOA 30-45 min infusion 5 mcg/kg/hr
51
Hydromorphone
1.5 mg= 10mg Morphine
52
Midazolam IV sedation
1-2.5 mg IV bolus
53
Flumazanil
0.2mg IV (titrate 0.1mg to effect, max 1mg)
54
Remifentanil (infusion)
0.05-2 mcg/kg/min
55
Remifentanil (sedation with benzo)
0.05-0.1 mcg/kg/min
56
Remifentanil (pre-induction)
1 mcg/kg over 60-90sec
57
Midazolam (peds, sedation and anxiolysis)
0. 5 mg/kg PO 30 min before case | 0. 05-1 mg/kg IM
58
Fentanyl analgesia/sedation
1-2 mcg/kg
59
Fentanyl induction
2-20 mcg/kg 1-5mcg/kg balanced- 1.5-3 mcg/kg decreases IA by 50%
60
Diazepam anticonvulsant
0.1 mg/kg IV
61
Diazepam IV sedation
0.05-0.15 mg/kg
62
Sufentanil O-P-D
o- 3min p- 7min d- 0.5-1hrs
63
Diazepam Induction
0.3-0.5 mg/kg
64
Diazepam (sedation and anxiolysis PO)
10-15 mg PO
65
Meperidine O-P-D
o- <1min p- 5-7min d- 2-3hrs
66
Morphine O-P-D
IV: o- 5min p-15-20min d- 3-4hrs IM: o- 15-30min p- 45min
67
Fentanyl O-P-D
o- 2min p- 5-7min d- 45min
68
Alfentanil O-P-D
o- 30 sec p-1.5-2min d- 15min
69
Remifentanyl O-P-D
o- 0.5-1min p- 1.5-2min d- 10min
70
Neostigmine
Up to 0.07 mg/kg (but no more than 5 mg total dose)
71
Pyridostigmine
up to 0.35 mg/kg (up to 20 mg in adults)
72
Endrophonium
1 mg/kg
73
Physostigmine
0.03 mg/kg
74
Atropine (premedication)
-0.01-0.04 mg IM (up to 0.4-0.6 mg total, adults)
75
Atropine (minimize muscarinic effects of anticholiesterases)
up to 10 mcg/kg (with endrophonium)
76
Scopalamine (premedication)
0.4-0.6 mg/kg IM
77
Glycopyrrolate (premedication)
up to 0.3 mg IM
78
Glycopyrrolate (minimize muscarinic effects of anticholinesterases)
0.01-0.12 mcg/kg
79
``` Neostigmine: 1 mg 2 mg 3 mg 4 mg 5 mg ```
Glycopyrrolate: 0. 2 mg (4/4 with ST) 0. 4 mg (4/4) 0. 6 mg (3/4) 0. 7 mg (2/4) 0. 8 mg (1/4)
80
Physiostigmine (treatment central anticholinergic syndrome)
15-60 mcg/kg IV

Pharmacology (9 decks)

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