Dr. Zachow - Last 3 Lectures Flashcards
WHat is responsible for a rise in systolic BP? Diastolic?
Systolic = CO, so like exercise Diastolic = Vasoconstriction so like some sort of blockage
Pulse Pressure
Systolic - Diastolic
If acute venodilation occurs, how will it be compensated for to return to normal RAP?
Increased inotropy
What is the bodies response to an increase in arteriolar dilation?
Initially: There will be an increase in dilation on the venous side to accommodate the all of the blood rushing into the veins. This will cause you to. Move over on the cardiac. Function curve.
Later: After a few seconds, the SNS will be turned on, which will increase inotropy (beta1) as well as arteriolar constriction (alpha1), which will create a new cardiac function curve with a higher CO, increased MAP (closer to basal), and a RAP closer to basal
Much later: Your body will decrease urine output to increase fluid volume, which will increase Pmcf which will increase Pa, and bring things back to normal.
What would be the bodies reaction if you had a significant loss in plasma volume?
SNS would turn on to increase inotropy and vasoconstriction via alpha1 and beta1. Graphically, you would see an increased cardiac function graph and decreased slope on the arteriolar side. This will lead to an increased CO, MAP,
WHat happens during exercise?
Initially there is vasoconstriction and inotropy. This increases CO, MAP, and decreases RAP. Soon though the vasodilatory metabolites kick in. When this happens, we see vasodilation of the arteriolar side, which causes an increase in slope. When this happens, we move over on our starling curve to the right to compensate for these things - so more cardiac function. Because we have vasodilation, we will also have increased venous return, which will cause a dilation on the venous side. Because of all of these things, we will have a decreased MAP closer to Normal…
Compliance =
Change in Volume / Change in Pressure
