Dr.Almaslec#5 Flashcards
(29 cards)
Which cytokines are classified as proinflammatory mediators?
TNF-α
Pavementing refers to leukocytes moving toward the center of blood vessels.
False
Which complement fragments increase vascular permeability?
C3a and C5a
(“Acute inflammation usually lasts for weeks to months. (True/False)”
False
What chemical factor causes vasodilation and capillary permeability during inflammation?
“Prostaglandins”)
Which leukocyte process involves pseudopodia extending through capillary walls?
Emigration or diapedesis
(“Celsus identified four cardinal signs of inflammation. (True/False)”
True
What is the fifth cardinal sign of inflammation added by Galen?
“Loss of function”)
Histamine is primarily stored in which types of cells?”
Platelets
Chronic inflammation involves mainly which immune system branch?
Adaptive immune system
The inflammatory response ends when the offending agent persists.
False
What is the main cause of slow and sustained constriction of bronchioles?
Leukotrienes
Leukocyte chemotaxis is guided by cytokines
chemokines, bacterial debris
Which mediator induces platelet aggregation?
Platelet-activating factor (PAF)
Bradykinin increases capillary permeability and causes pain.
True
Which step comes first in the inflammatory response?
Recognition of the injurious agent
Which inflammatory mediator is known for promoting fever?
Prostaglandins
Phagocytosis by macrophages first induces the production of which cytokines?
IL-1
Complement fragments C3a and C5a inhibit neutrophil migration.
False
Calor refers to swelling in the tissue.
False
Which process involves leukocytes adhering to the blood vessel walls?
pavementing.
The matrix around blood vessels plays no role in inflammation.
False
Which two processes often occur during chronic inflammation?
Angiogenesis and fibrosis
The cellular response of acute inflammation involves granulocytes and monocytes.
True
