Drolinger

Question 1

Articane

Answer 1

7.0 mg/kg

Question 2

Amide

Answer 2

p450

Question 3

Ester

Answer 3

plasma (blood) by enzyme pseudochlinesterase

Question 4

Uncharged form diffuses across ___ through nerve sheath.

Answer 4

membrane

Question 5

Charged __ inside ion channel protein at receptor site

Answer 5

binds

Question 6

Maximum dose of epinephrin

Answer 6

0.02 mg/appointment

Question 7

2 most imp. factors involved in LA are unionized form that passes through the membrane and the ionized form that binds at the receptor site in the membrane channel.

Answer 7

True

Question 8

The pka determines the rate of onset of local anesthetic, bucivacine (pka 8.1) has a more RAPID onset of action than articaine (pka 7.8)
(Slide 10, 16)

Answer 8

True; false

Question 9

Lidocaine is (slide 2,18)

Answer 9

metabolized b y micrososomal P-450 enzymes in the liver

Question 10

Max recommendeddosage for 4% articaine (septocaine) 1:100,000 epi? Slide 32

Answer 10

7.0 mg/kg

Question 11

The NAID will sig. reduce for post acute pain

Answer 11

True