Bupropion
(Zyban, Welbutrin); Atypical antidepressant - Blocks NE, DA uptake (Not 5HT) - Weak nicotinic receptor antagonist; May reduce nicotine use, No CNS depression, Sexual dysfunction, Seizure threshold lowered, Insomnia, Agitation, Pruritis, Bruxism; MAY PRESCRIBE TO PREVENT ORAL CANCER, Chemically related to canthinones in Khat
Canthinones and Bath Salts
Khat plants, More toxic; MDPV, Mephedrone, Meththylone, Flakka = Alpha PVP; Pleasant experience with sociability and sex drive sought with paranoia, agitation, tachycardia, delusion, hallucination, psychosis, seizures, violent behavior, amnesia, death - Bruxism and Dry mouth; Hospitalizations; Benzodiazepine treatment (Diazepam/Lorazepam)
Varenicline
Nicotine receptor partial agonist: alpha4-beta2, limits nicotine from further stimulating receptors, Moderates DA release in nucleus accumbens and cortex to reduce withdrawal symptoms; Nausea, vomit, sleep disturbance, Neuropsychiatric effects - Behavior, agitation, mood and suicidal ideation
Ethyl
Ch3Ch2OH (ethanol); Methanol/Ethylene glycol detox - Treat stroke(Caffinol)
Methyl
Ch3OH (methanol, wood alcohol) - Dental bench torch fuel
Isopropyl
Ch3Ch3ChOH (rubbing alcohol) - Disinfectant and cleansing agent
Benzodiazepine
Manage Ethanol dependence, Sedation, Seizures, Stage withdrawl; Antipsychotics - Hallucinations, Clonidine - Autonomic hyperactivity
Disulfiram
(Antabuse); Chelates metal ion cofactors necessary for acetaldehyde dehydrogenase activity; N&V, Flushing, Headache, Sweating, Hypotension, Confusion; Slow elimination (Negative reinforcement for drinking)
Naltrexone
(ReVia); Opioid receptor antagonist, Reduce craving
Acamprosate
(Campral); Competitive inhibitor of NMDA Glutamate receptor
