DRUG CLASSIFICATION

Question 1

Classes of anticancer drugs

Answer 1

Alkylating agents
Antimetabolites
Cytotoxic antibiotics
Plant-Derived Products
Enzymes
Hormonal agents
Miscellaneous agents
Monoclonal antibodies
Protein Kinase inhibitors
Immunomodulating agents
Cellular growth factors

Question 2

Alkylating agents

Answer 2

Nitrogen mustards
Nitrosureas
Alkyl sulfonates
Platinum compounds
Ethylenimines and methylmelamines
Triazenes

Question 3

Nitrogen mustards

Answer 3

Bendamustine
Etramustine
Chlorambucil
Cyclophosphamide
Mechlorethamine
Melphalan
Ifosfamide

Question 4

Nitrosureas

Answer 4

Carmustine
Lomustine
Semustine
Streptozocin

Question 5

Alkyl sulfonates

Answer 5

Busulfan

Question 6

Ethylenimines and methylmelamines

Answer 6

Thiotepa
Altretamine (hexamethyl melamine)

Question 7

Triazines

Answer 7

Dacarbazine
Procarbazine
Temozolamide

Question 8

Platinum compounds

Answer 8

Cisplatin
Carboplatin
Oxaliplatin

Question 9

Antimetabolites

Answer 9

Folate antagonists
Purine analogues
Pyrimidine analogues

Question 10

Folate antagonists

Answer 10

Methotrexate
Premetrexed
Raltitrexed

Question 11

Pyrimidine analogues

Answer 11

Capecitabine
Cytarabine
Decitabine
Gemcitabine
Azacitidine
Fluorouracil
Tegafur

Question 12

Purine analogues

Answer 12

Cladribine
Clofarabine
Fludarabine
Azathioprine
Mercaptopurine
Nelarabine
Pentostatin
Thioguanine

Question 13

Cytotoxic antibiotics

Answer 13

Anthracyclines
Bleomycin
Mitomycin C
Dactinomycin
Plicamycin
Trabectedin

Question 14

Types of Plant-derived cancer drugs

Answer 14

Taxanes
Vinca alkaloids
Camptothecins
Epipodophyllotoxins

Question 15

Taxanes

Answer 15

Paclitaxel
Docetaxel
Cabazitaxel

Question 16

Vinca alkaloids

Answer 16

Vinblastine
Vincristine
Vindesine
Vinflurine
Vinorelbine

Question 17

Camptothecins

Answer 17

Irinotecan
Topotecan
Belotecan

Question 18

Epipodophyllotoxins

Answer 18

Etoposide
Teniposide

Question 19

Enzymes used in cancer

Answer 19

L-asparaginase

Question 20

Classification of Hormonal agents used in cancer

Answer 20

Agonists:
Glucocorticoids
Estrogens
Progestins
Somatostatin analogues

Antagonists:
Antiestrogens
Antiandrogens
5-alpha reductase inhibitors
GnRH analogues

Question 21

Glucocorticoids

Answer 21

Prednisolone
Dexamethasone

Question 22

Estrogens

Answer 22

Diethylstilbesterol
Ethinylestradiol

Question 23

Progestins

Answer 23

Megestrol
Northisterone
Medroxyprogesterone

Question 24

GnRH analogues

Answer 24

Goserelin
Naferelin
Buserelin
Leuprorelin
Triptorelin
Leuprolide

Question 25

Somatostatin analogues

Answer 25

Octreotide Lanreotide Pasireotide

Question 26

Antiandrogens

Answer 26

Flutamide Bicalutamide Cyproterone

Question 27

Antiestrogens

Answer 27

Tamoxifen Toremifene Fulvestrant

Question 28

Aromatase inhibitors

Answer 28

Steroidal Exemestane Formestane Non-steroidal Anastrazole Letrozole

Question 29

5-alpha reductase inhibitors

Answer 29

Finasteride Dutasteride

Question 30

GnRH antagonists

Answer 30

Abarelix Degarelix Cetrorelix Ganirelix Elagolix Relugolix

Question 31

Protein kinase inhibitors

Answer 31

Imatinib Erlotinib Soratinib Crizotinib Axitinib Dasatinib Sunitinib Gefitinib Everolimus Sorafenib Tacrolimus

Question 32

Monoclonal antibodies

Answer 32

Panitumumab Trastuzumab Brentuximab Ofatumumab Rituximab Bevacizumab Catumaxomab Nivolumab Pembrolizumab Atezolimumab Ipilimumab

Question 33

Immunomodulating agents

Answer 33

Levamisole Interferons Interleukins

Question 34

Cellular growth factors

Answer 34

Filgrastim Sargromastim

Question 35

Miscellanous

Answer 35

Hydroxyurea Mitotane Mitoxantrone Bexarotene