Drug Effects

Question 1

Absorption Drug Effects

Answer 1

pH changes, alteration of GI motility

Question 2

Distribution Drug Effects

Answer 2

Plasma protein competition

Question 3

Metabolism Drug Effects

Answer 3

Enzyme inhibitors, inducers

Question 4

Elimination Drug Effects

Answer 4

Inhibition of active secretion in renal tubules

Question 5

Overdose

Answer 5

Exceed therapeutic window- toxicity

Question 6

Allergy

Answer 6

Adverse reaction from previous expose to a particular chemical. Mediated by immune system

Question 7

Anaphylaxis

Answer 7

Acute, life threatening allergic reaction involving multiple systems

Question 8

Idiosyncratic

Answer 8

Abnormal reactivity to a chemical that is peculiar to a particular individual. May be extreme sensitivity to low doses or insensitivity to high doses

Question 9

Excessive Pharmacologic Effect

Answer 9

Take a drug for a desired effect and get undesired effect- sleeping pills for sleep cause drowsiness the next day

Question 10

Mutagenic

Answer 10

Capable of inducing genetic mutation.

Question 11

Carcinogenic

Answer 11

Causing cancer

Question 12

Teratogenic

Answer 12

Causing developmental malformations