Drug Formulation

Question 1

What is drug formulation?

Answer 1

Make up of tablet/oral dose

Question 2

What are the 2 general routes of drug administration?

Answer 2

• Enteral

- Parenteral

Question 3

What is enteral drug administration?

Answer 3

Via the gastrointestinal tract

Question 4

What is paraenteral drug administration?

Answer 4

Any route that is not via the GI tract

Question 5

Give 3 examples of enteral drug routes

Answer 5

• Oral
• Sublingual
• Rectal

Question 6

What are the units for oral drug routes?

Answer 6

Grams

Question 7

What are the units for sublingual drug routes?

Answer 7

Grams

Question 8

What are the units for rectal drug routes?

Answer 8

Grams/litre

Question 9

What is the main issue with enteral drug routes?

Answer 9

Significant 1st pass effect

Question 10

What is the advantage of an oral drug route?

Answer 10

Easy administration

Question 11

What are the disadvantages of oral drug routes? (3)

Answer 11

• Slow in action
• Compliance
• Many situations where drug can’t be administered
• 1st pass effect

Question 12

Give 3 patient situations where drugs can’t be orally administered (3)

Answer 12

• Vomiting
• Unconsciousness
• Seizure

Question 13

Give 2 patient situations where compliance with oral administration is an issue (2)

Answer 13

• Older people confusion

- Mental health conditions, patient doesn’t want to