Drug Interactions with Receptors and Ion Channels

Question 1

Adenosine

Answer 1

Adenosine R agonist

Question 2

Atropine

Answer 2

Non-selective muscarinic cholinergic R antagonist

Question 3

Bay K 8644

Answer 3

Calcium agonist

Question 4

Benzilylcholine mustard

Answer 4

Non-selective irreversible muscarinic cholinergic R antagonist

Question 5

Benzocaine

Answer 5

Voltage-gated Na+ channel blocker

Question 6

α-bungarotoxin

Answer 6

Irreversible, selective for NMJ, competitive nicotinic acetylcholine R antagonist

Question 7

Cholera toxin

Answer 7

αs subunit GTPase activity inhibitor

Question 8

Diltiazem

Answer 8

Myocyte voltage-gated calcium channel blocker

Question 9

D-tubocurarine

Answer 9

Non-selective nicotinic cholinergic R antagonist

Question 10

Ethinylestradiol

Answer 10

Oestrogen R agonist

Question 11

Glibenclamide

Answer 11

Sulphonylurea R agonist

Question 12

Isoprenaline

Answer 12

Non-selective β-adrenoceptor agonist

Question 13

Lidocaine/lignocaine

Answer 13

Na+ channel block

Question 14

Minoxidil

Answer 14

K+ (ATP) channel opener

Question 15

Nicorandil

Answer 15

K+ (ATP) channel opener

Question 16

Nifedipine

Answer 16

L-type Ca2+ channel blocker

Question 17

Norethisterone

Answer 17

Progesterone R agonist

Question 18

Pertussis toxin

Answer 18

αi subunit inhibitor

Question 19

Prednisolone

Answer 19

Short acting lucocorticoid R agonist

Question 20

Quinidine

Answer 20

Na+, Ca2+, K+ channels blocker

Question 21

Spironolactone

Answer 21

Competitive • aldosterone/mineralocorticoid R antagonist

Question 22

Tamoxifen

Answer 22

Oestrogen R antagonist

Question 23

Tetrodotoxin

Answer 23

Na+ channel blocker

Question 24

Tyrphostins

Answer 24

Tyrosine kinase inhibitor

Question 25

Verapamil

Answer 25

Myocyte Ca2+ channel blocker