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Hospital Pharmacy > Drug List 5 > Flashcards

Drug List 5 Flashcards

1
Q

Aminosteril® 5%

A

Amino acid

Parenteral nutrition

Solution (Infusion)

MOA: provide nutrition into the body by supplying needed amino acid
CI: amino acid metabolism problems
PC: Sulfite allergy
ADR: unexplained weight gain

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2
Q

Amphotret®

A

Amphotericin B

Invasive fungal infection (Candidiasis)

lyophilized powder (Intravenous)

MOA: Binds to ergosterol causing intracellular leakage
CI: Hypersensitivity
PC: not be used to treat noninvasive forms of fungal disease
ADR: multiple organ failure

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3
Q

Marcaine®

A

Bupivacaine

Labor pain

Solution, Liposomal suspension (Intraspinal)

MOA: Binds to Sodium channels to block sodium influx to nerve cells, blocking nerve impulse
CI: —
PC: convulsions due to systemic toxicity
ADR: convulsions

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4
Q

Sandimmune®

A

Cyclosporine

Immunosuppression in organ transplant

Capsule, Solution (Oral)
Emulsion (Ophthalmic)

MOA: Inhibits the production and release of interleukin II
CI: Rheumatoid arthritis
PC: Renal impairment
ADR: hepatitis

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5
Q

Dextran 70

A

RescueFlow®

hypovolemic shock

Solution (infusion)

MOA: nonprotein colloid and plasma volume expander, It reduces blood viscosity and has antiplatelet effect
CI: bleeding disorders
PC: hemorrhage
ADR: Severe anaphylactic reactions

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6
Q

Epogen®

A

Epoetin α

chronic kidney disease

Solution (IV, SC)

MOA: same actions as endogenous erythropoietin which maintain a healthy amount of red blood cells
CI: hypertension
PC: increase the risk of Cardiovascular events
ADR: transient ischemic attack,

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7
Q

Lanexat®

A

Flumazenil

Benzodiazepine poisoning

Solution (Intravenous)

MOA: Competitive inhibitor of GABA
CI: —
PC: Benzodiazepine reversal may result in seizures.
ADR: Abnormal hearing

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8
Q

Pedia-lax®

A

Chewable tab: Magnesium Hydroxide

Supp: Liquid Glycerin

Oral Soln: docusate Na

Enema: Saline

Constipation (OTC)

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9
Q

Hepabig®

A

Hepatitis B Immunoglobulin

prophylaxis to hepatitis B

Solution (Intramuscular)

MOA: passive immunization for individuals exposed to the hepatitis B virus by binding to the surface antigen
CI: Allergy
PC: coagulation disorders
ADR: Tremor and hypotension

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10
Q

Heparin

A

Hepastar 5000®

thromboembolic disorders

Solution (IV, SC)

MOA: enhancing the inhibition rate of clotting proteases, antithrombin III
CI: —
PC: Hemorrhage may occur
ADR: —

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11
Q

Venofer®

A

Iron sucrose

iron-deficiency anemia

Solution (Intravenous)

MOA: iron is incorporated into hemoglobin to mature into red blood
CI: Iron overload
PC: only be administered
when personnel immediately available
ADR: severe hypotension.

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12
Q

Forane®

A

Isoflurane

Induction of general anesthesia

Solution (Inhalation)

MOA: halogenated methyl ester that
produces profound respiratory depression and alter activity of neuronal ion channels
CI: history of hepatitis
PC: Increased intracranial pressure
ADR: —

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13
Q

Keppra®

A

Levetiracetam

Epilepsy

Tablet, Solution (Oral)
Solution (IV)

MOA: facilitation of GABA-ergic inhibitory transmission by displacing negative modulators
CI: Hypersensitivity
PC: pre-existing cardiac disease
ADR: Suicidal ideation

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14
Q

Lipidem®

A

Atorvastatin

Hyperlipidemia

Tablet (Oral)

MOA: selective, competitive inhibitor of HMG-CoA reductase preventing convertion to mevalonate, limiting cholesterol biosynthesis.
CI: Active liver disease,
PC: Liver dysfunction
ADR: pancreatitis

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15
Q

Gelofusine®

A

Succinylated gelatin

hypovolemia

Solution (Intravenous)

MOA: colloidal plasma substitutes that exert osmotic pressure to
maintain circulatory volume.
CI: Hypervolemia;
PC: Renal insufficiency
ADR: hypertension,

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16
Q

Nubain®

A

Nalbuphine

Severe pain (DD - Sched 4)

Solution (IV, IM, SC)

MOA: Binds to opiate receptors to produce analgesic effects
CI: bronchial asthma
PC: respiratory depression
ADR: bradycardia

17
Q

Zofran®

A

Ondansetron

nausea and vomiting in chemotherapy

Solution (IV, IM)

MOA: selective 5-HT3 receptor inhibitor blocking its effect on vagal afferent nerves
CI: use of apomorphine
PC: gastric distention.
ADR: Abdominal pain

18
Q

Diprivan®

A

Propofol

Induction of general anesthesia;

Emulsion (Intravenous)

MOA: GABA inhibitorand associated with minimal respiratory depression
CI: Hypersensitivity to eggs
PC: Lipid disorders
ADR: Myoclonus

19
Q

Herceptin®

A

Trastuzumab

breast cancer

lyophilized powder, Solution (IV, SC)

MOA: monoclonal antibody that binds with HER-2 protein and inhibiting proliferation of cells
CI: Hypersensitivity to Chinese
hamster ovary (CHO) cell proteins
PC: Hazardous agent
ADR: blood coagulation disorder

20
Q

Vastarel® MR

A

Trimetazidine

Stable angina

Tablet (Oral)

MOA: A fatty acid oxidation (pFOX) inhibitor that alters metabolism to
maintain intracellular ATP levels in ischemic regions
CI: Parkinson disease;
PC: Renal impairment
ADR: Parkinsonian symptoms

Hospital Pharmacy (9 decks)

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