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Nutrition Support Certification Exam 2013 > Drug-Nutrient Interactions > Flashcards

Drug-Nutrient Interactions Flashcards

(91 cards)

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1
Q

Ampho B

A

dec Ca+,Vit D, folic acid, zinc

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2
Q

Dilantin

A

Dec Vit D, folic acid

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3
Q

ABX

A

Dec Vit K

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4
Q

Heparin and coumadin

A

Avoid Large doses Vit C

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5
Q

Zinc decreases with

A

albumin, Vit A, infection, worsens hepatic dysfunction, dec resp fx, muscle fx and glucose intolerance

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6
Q

Add zinc in what diagnosis

A

TBI, hypermetabolism, GI losses, wounds

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7
Q

Inc CRP does what to zinc levels

A

dec 50%

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8
Q

Decreased Copper with what food/vits

A

phytates (whole grains, legumes, nuts/seeds), fiber, zinc, Fe, large doses Vit C

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9
Q

Dec Vit D with

A

Decreased Copper in malnourished

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10
Q

Increased zinc when

A

decreased Copper

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11
Q

Diarrhea depletes

A

K+ & Magnesium

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12
Q

Prolonged diarrhea depletes

A

Selenium (SBS)

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13
Q

Low Magnesium- what do you decrease in diet

A

fat binds to Magnesium and increases stool output

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14
Q

Neomycin- (ABX) does what to GI

A

partially villous atrophy and steatthorea

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15
Q

Cholestyramine causes what vitamin deficiency

A

def in ADEK

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16
Q

ACE

A

In Ca+, K+, Na and Dec PO4

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17
Q

Sulfasalazine (UC, RA)

A

Dec body stores folic acid, B12 with large doses long term

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18
Q

Dilantin

A

dec absorption of folic acid, Vit D, Vit K in fetus

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19
Q

Valproic Acid

A

carnitine

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20
Q

ABX aminoglycosides-tobra, gent

A

Dec Mg & K+= hearing loss

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21
Q

Cyclosporine

A

no grapefruit

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22
Q

Albuterol (beta antagonists)

A

Dec K+

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23
Q

Loop diuretics (lasix)

A

Dec Mg, K, Ca

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24
Q

Thiazide diuretics (Hctz)

A

decreased urine excretion of Ca

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25
Jtube drugs not absorbed
carbomazepine (anti-seizure), cipro, Ca, Mg, antacid, Fe, coumadin hold 2 hr before/after
26
MAOI
no tyramine (aged cheese, salami, sauerkraut, soy, tap beer, wine, vermouth)
27
Chemo (patins)
loss Mg, Dec Ca-not respond to suppl
28
Decrease FAt soluble vits
statins, mineral oil laxatives
29
High protein
inc excretion of Calcium
30
Flagyl (metronidazole)
avoid ETOH and exilir
31
Ring worm med (Griseofulvin)
No ketogenic diet
32
Fatty foods with Gemfibozil
decreases activity
33
Lithium
HIgh salt=lithium excreted, Low salt= lithium toxic
34
Digoxin
No fiber TF- watch s/s, no licorice which incrases BP naturally
35
Zantac
Dec absorption Fe
36
Average Vit K in diet
90-118 mcg/day (<100mcg per 1000 cals)
37
Levothyroxine (sythroid) decreased absorption with what type of protein
soy
38
Which mins have high osmolality and must be spaced out
K, PO4, Mg
39
High osmolar diuretic that must be diluted
lasix= 3900 with 49% sorbitol
40
ranitidine in PN with 12 hr cycle
another does for additional 12 hrs off PN
41
Iron Dextran IV
no lipid in PN, over 18 hrs
42
Reglan (metroclopramide) helps
nausea with Hyperemesis
43
Ginger/B6 helps
nausea with Hyperemesis
44
triamterene
K+ sparing diuretic
45
ADH released when what happens to serum
Inc osmolality
46
Large doses Vit C, Avoid with these meds/vits
heparin, coumadin and Copper
47
Low Mg, decrease this in diet
fat- it binds with Mg to make it lower
48
HD- lose these vits
water soluble B and Fe
49
Inflammatory mediators include
cytokines, TNF, interleuken-1
50
Microcytic, hypochromic anemia
Fe, Copper
51
Macrocytic anemia
Folic acid
52
Megaloblastic anemia
B12, Folic acid
53
Micrcytic
B6
54
@ risk of B6 deficiency
HD, elderly, steroids, anticonvulsants, ETOH
55
Decreased Vit D s/s
muscle weakness, High BP, HL
56
Fe absorbed where?
proximal jejunum
57
Hold TF with these meds
theophylline, cipro, dilantin, coumadin
58
metheotrexate can bind with this vit
folate
59
Decreased absorption of Folic acid with these factors
impaired bile, change jejunal pH
60
Meds that dec absorption of Folic acid
dilantin, ampho B, sulfasalazine, choestyramine, PD dialysis
61
citrate, gluconate, lactate acetate are
bicarbs
62
SIADH
euvolemia, total body inc, conc urine
63
Inc ADH
conc urine
64
Independent predictor for m/m in critically ill
alb < 2.6
65
Starvation
dec Gluc, ketosis, lipolysis
66
Stress Malnutrition
Hypermetabolism, Inc Gluc, lipolysis
67
Malnurition is what wt loss criteria
10% wt loss UBW x 6 months, equal or greater than 5% wt loss x 1 month
68
Jtube feeds, check this vit level
Fe
69
Overfeeding
resp acidosis
70
TF syndrome
Hi BUN/creat, Inc Na, dehydration s/t HI PRO/low fluid
71
Hypocaloric with Obese
BMI > 30, 22 cals/kg
72
GFR for ESRD
< 15cc/min or 1.73m2
73
PRO for PD Dialysis
1.2-1.3g/kg/d
74
CF @ risk what vit def
fat soluble d/t panc insufficiency.
75
Essential Fatty Acid sources
veg oils- canola, flaxseed, walnut, fish
76
SB overgrowth
D lactic acidosis
77
Octreotide
refractory diarrhea
78
SB 150-200 cm
significant losses
79
WHO oral rehydration soln
CHO 40g, NA 90g, K 20, Osmo 311
80
Normal length small bowel
600 cm
81
Normal length colon
150
82
SBS without colon
add salt, high fluid/Na output, no simple sugars, isotonic/high Na ORS
83
Inflammatory hormones
epinephrine, glucogan, cortisol
84
Body process with Acute Response Phase
glucogenolysis, gluconeogenesis, liplysis, proteolysis
85
SBS with colon
Intol high fat, hypotonic fluid, bacterial overgrowth, oxalate kidney stones, unabsorbed bile salts damage colon--secretory diarrhea.
86
Diet for SBS with colon
small freq meals, low fat, complex CHO, limit simple sugars, MCT, EFA, soluble fiber, low oxalates, sip ORS
87
Diet for SBS without colon
small freq meals, avoid low cals/high fiber, restrict simple sugars, add salt, sip isotonic/high Na ORS,suppl lytes with po /IV, antiperistaltic agents a meals, H2 blockers, PPI
88
Most widely tool to measure generic healthy status
SF 36
89
Fat increases blood flow to
GI
90
Lower threshold with initiation of PN in this population
elderly
91
GAstric Bypass supple these vits
B12, B1, zinc, copper

Nutrition Support Certification Exam 2013 (11 decks)

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