drug reactions Flashcards

(48 cards)

1
Q

coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing

A

vancomycin
adenosine
niacin
CCBs

VANC

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3
Q

dilated cardiomyopathy

A

doxorubicin (adriamycin)

daunorubicin

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4
Q

torsades de pointes

A

class III (sotalol) and class IA (quinidine) antiarrythmics

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5
Q

agranulocytosis

A

Agranulocytosis Could Certainly Cause Pretty Major Damage

Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone
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6
Q

aplastic anemia

A
chloramphenicol
benzene
NSAIDs
propylthiouracil
methimazole
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7
Q

direct coombs-positive hemolytic anemia

A

methyldopa

penicillin

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8
Q

gray baby syndrome

A

chloramphenicol

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9
Q

hemolysis in G6PD-deficient patients

A

hemolysis IS PAIN

Isoniazid
Sulfonamides
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
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10
Q

megaloblastic anemia

A

having a BLAST with PMS

Phenytoin
Methotrexate
Sulfa drugs

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11
Q

thrombotic complications

A

OCPs

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12
Q

cough

A

ACE-I

*use ARBs (-sartans) instead

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13
Q

pulmonary fibrosis

A

it’s hard to BLAB when you have pulmonary fibrosis

BLeomycin
Amiodarone
Busulfan

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14
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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15
Q

focal to massive hepatic necrosis

A

liver HAVAc

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

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16
Q

hepatitis

A

isoniazid

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17
Q

pseudomembranous colitis

A

clindamycin

ampicillin

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18
Q

adrenocortical insufficiency

A

glucocorticoid withdrawal (HPA suppression)

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19
Q

gynecomastia

A

Some Drugs CrEate Awkward Knockers

Spironolactone
Digitalis
Cimetidine
Estrogens
chronic Alcohol use
Ketoconazole
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20
Q

hot flashes

A

tamoxifen

clomiphene

21
Q

hyperglycemia

A
niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids
22
Q

hypothyroidism

A

lithium
amiodarone
sulfonamides

23
Q

fat redistribution

A

glucocorticoids

protease inhibitors

24
Q

gingival hyperplasia

A

phenytoin

verapamil

25
gout
furosemide thiazides niacin cyclosporine
26
myopathies
Fish N CHIPS Give you myopathies ``` Fibrates Niacin Colchicine Hydroxychloroquine IFN-a Penicillamine Statins Glucocorticocoids ```
27
osteoporosis
corticosteroids | heparin
28
photosensitivity
SAT for a photo Sulfonamides Amiodarone Tetracycline
29
rash (SJS)
bad rash after a PEC SLAPP ``` Penicillin Ethosuximide Carbamazepine Sulfa drugs Lamotrigine Allopurinol Phenytoin Phenobarbital ```
30
SLE-like syndrome
it's not HIPP to have lupus Hydralazine Isoniazid Procainamide Phenytoin
31
teeth (kids)
tetracyclines
32
tendonitis, tendon rupture, cartilage damage
fluoroquinolines
33
diabetes insipidus
lithium | demeclocycline
34
fanconi's syndrome
expired tetracycline
35
hemorrhagic cystitis
cyclophosphamide ifosfamide (prevent by coadministering with mesna)
36
interstitial nephritis
methicillin NSAIDs furosemide
37
SIADH
carbamazepine | cyclophosphamide
38
cinchonism
quinidine | quinine
39
parkinson-like syndrome
antipsychotics reserpine metoclopramide
40
seizures
with seizures, I BITE My tongue ``` Isoniazid Bupropion Imipenem/cilastatin Tramadol Enflurane Metoclopromide ```
41
tardive dyskinesia
antipsychotics
42
antimuscarinic
atropine TCAs H1-blockers neuroleptics
43
disulfiram-like reaction
metronidazole certain cephalosporins procarbazine 1st gen sulfonureas
44
nephrotoxicity/ototoxicity
aminoglycosides vancomycin loops diuretics cisplatin
45
P450 inducers (+)
Most Barbies Steals Phen-phen and Refuse Greasy Carbs Chronically ``` Modafinil Barbiturates St. John's wort Phenytoin Rifampin Griseofulvin Carbamazepine Chronic alcohol use ```
46
P450 inhibitors (-)
MAGIC RACKS in GQ ``` Macrolides Amiodarone Grapefruit juice Isoniazid Cimetidine Ritonavir Acute alcohol abuse Ciprofloxacin Ketoconazole Sulfonamides Gemfibrozil Quinidine ```
47
Sulfa drugs
Popular FACTSSS ``` Probenecid Furosemide Acetazolamide Celecoxib Thiazides Sulfonamide antibiotics Sulfasalazine Sulfonylureas ```
48
Sulfa drugs: allergy
``` fever UTI pruritic rash Stevens-Johnson syndrome hemolytic anemia thrombocytopenia agranulocytosis urticaria ``` mild => life threatening