Drug Times

Question 1

Adrenaline

Answer 1

IV
Onset: 30 secs
Peak: 3-5 minutes
Duration: 5-10 minutes 
IM
Onset: 30-90 secs
Peak: 4-10 Minutes
Duration: 5-10 Minutes

Question 2

Aspirin

Answer 2

Onset: N/A
Peak: N/A
Duration: 8-10 days

The anti-platelet effects of aspirin persist for the natural life of the platelets

Question 3

Dexamethasone

Answer 3

Onset: 30-60 minutes
Peak: 2 hours
Duration: 36-72 hours

Question 4

Dextrose

Answer 4

IV:
Onset: 3 minutes
Peak: N/A
Duration: Depends on severity of hypoglycaemic episode

Question 5

Fentanyl

Answer 5

Onset: Immediate
Peak: < 5 minutes
Duration: 30-60 minutes

IN effects:
Peak: 2 minutes

Question 6

Glucagon

Answer 6

Onset: 5 minutes
Peak: N/A
Duration: 25 minutes

Question 7

GTN

Answer 7

S/L:
Onset: 30secs - 2mins
Peak: 5-10 mins
Duration: 15-30 minutes

IV effects:
Onset: 30 secs-1min
Peak: 3-5 minutes
Duration: 15-30 minutes

Transdermal effects:
Onset: up to 30 mins
Peak: 2 hours

Question 8

Heparin

Answer 8

Onset: Immediate
Duration: 3-6 hours

Plasma half life of Heparin is 60 mins. Any pt receiving a bolus dose will require a repeat dose if travel time to PCI is > 1hr

Question 9

Ipratropium Bromide

Answer 9

Onset: 3-5 minutes
Peak: 1.5 - 2 hours
Duration: 6 hours

Question 10

Ketamine

Answer 10

IV:
Onset: 30 secs
Duration: 5-10 minutes

IN:
Onset: 5 mins
Peak: 20 mins
Duration: 45 minutes

Question 11

Lignocaine

Answer 11

Onset: 1-5 minutes
Duration: 1-1.5 hrs

Question 12

Methoxyflurane

Answer 12

Onset: after 8-10 breaths
Duration: 25 minutes

Question 13

Midazolam

Answer 13

IM:
Onset: 3-5 minutes
Peak: 15 minutes
Duration: 30 minutes

IV:
Onset: 1-3 minutes
Peak: 10 minutes
Duration: 20 minutes

Question 14

Morphine

Answer 14

IV:
Onset: 2-5 minutes
Peak: 10 minutes
Duration: 1-2 hours

IM:
Onset: 10-30 mins
Peak: 30-60 minutes
Duration: 1-2 hours

Question 15

Naloxone

Answer 15

IV:
Onset: 1-3 minutes
Peak: n/a
Duration: 30-45 minutes

IM:
Onset: 1-3 minutes
Peak: n/a
Duration: 30-45 minutes

Question 16

Olanzapine

Answer 16

Onset: 15 minutes
Duration: 12-24 hours

Question 17

Ondansetron

Answer 17

ODT:
Onset: 2 minutes
Peak: 20 minutes
Duration: 120 minutes

IV (slow push):
Onset: 5 minutes
Peak: 10 minutes
Duration: 2.5-6 hours

Question 18

Oxytocin

Answer 18

IM:
Onset: 2-4 minutes
Peak: n/a
Duration: 30-60 minutes

Question 19

Paracetamol

Answer 19

Onset: 30 minutes
Peak: n/a
Duration: 4 hours

Question 20

Prochlorperazine

Answer 20

Onset: 20 minutes
Peak: 40 minutes
Duration: 6 hours

Question 21

Salbutamol

Answer 21

Onset: 5-15 minutes
Peak: n/a
Duration: 15-50 minutes