Drugs Flashcards

(54 cards)

1
Q

Cardiac glycoside for CHF

A

Digoxin

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2
Q

Suppresses intracellular potassium

A

Digoxin

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3
Q

Digoxin at 3 ng/mL

A

Decrease ventricular depolarization, tachycardia

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4
Q

Half life for Digoxin

A

38 hours

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5
Q

Peak concentration of Digoxin

A

8-10 hours after oral dose

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6
Q

Propranolol halflife and toxic level?

A

3 hours and >100ng/mL

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7
Q

Digitoxin H and T

A

4-6 hours and greater than 25 ng/mL

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8
Q

Once Digoxin is metabolized in the liver, product is

A

Digitoxin

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9
Q

Elimination of Quinidine

A

Metabolism in the liver

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10
Q

Treatment of Quinidine

A

To treat cardiac arrhythmia

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11
Q

2 Most Common Fomulation

A

Quinidine sulfate and gluconate

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12
Q

Peak concentration of Quinidine Sulfate

A

2 hours after

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13
Q

Peak of Quinidine gluconate

A

4-5 hours after

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14
Q

Trough of Quinidine gluconate

A

1 hour after

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15
Q

Half life of Quinidine

A

5-12 hours

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16
Q

Active metabolite of quinidine

A

N acetylprocainamide

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17
Q

Metabolism of quinidine happens in liver through

A

Acetylation

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18
Q

Procainamide H and T

A

3-5 hours and 4-10ng/mL

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19
Q

Peak Procainamide

A

1 hour after intake

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20
Q

Used to treat cardiac arrhythmias

A

Procainamide

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21
Q

Another drug for cardiac arrhythmia with peak 1-2 hours after dose

A

Disopyramide

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22
Q

Not bound to proteins drug

23
Q

Lidocain H and T

A

2 hours and above 5.5

24
Q

Local anesthetic substance

25
Undergoes metabolism in liver through
dealkylation
26
Used to treat gram negative bacteria
Aminoglycosides
27
4 aminoglycosides
Gentamicin, tobramycin, amikacin, kanamycin
28
Administration route for Aminoglycosides
IM or IV
29
Elimination of aminoglycosides
Renal filtration
30
Toxic effects of Aminoglycosides
Ototoxicity and Nephrotoxicity
31
Treatment of gram positive bacteria
Vancomycin
32
Toxic effect of Vancomycin
Red man syndrome
33
Method of Vancomycin
Chromatography and Immunoassays
34
Specimen of Anticonvulsants
Trough serum concentration
35
Stabilizes the neuronal membranes
Phenobarbital
36
Block Na and Ca influx into neurons
Phenytoin
37
Other name for Phenytoin
Dilantin
38
Injectable form of phenytoin
Fosphenytoin
39
Anemia and Hypoalbuminemia
Phenytoin
40
Enhances GABA mediated inhibitory system
Valproic acid
41
Other name for Valproic acid
Depakene
42
Treatment for petit mal
Valproic acid
43
Acts by decreasing motor cortex activity
Ethosuximide
44
Other name for ethosuximide
Zarontin
45
Children with Lennox Gastaut Syndrome
Felbamate
46
Inhibitor of Lamotrigine
Valproic Acid
47
Indications: partial and generalizes seizures
Lamotrigine, Levetiracetam, Topiramate, Zonisamide
48
Mono therapy or together with AEDs for complex partial seizures
Gabapentin
49
Indications of mono therapy of practical seizures and in tonic clonic seizures
Oxcarbazepine
50
Treatment for partial seizuees
Tiagabine
51
Side effect: parasthesia
Tiagabine
52
Pins and needles sensation
Topiramate
53
Proform of phenobarbital
Primidone
54
Carbamazepine, other term
Tegretol