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Finals - Systems Paper > Drugs > Flashcards

Drugs Flashcards

1
Q

Lorazepam

A

Amnesia

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2
Q

Paroxetine in pregnancy

A

Congenital malformation

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3
Q

Lithium checked how often

A

12h after dose change, weekly, 3 monthly

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4
Q

Citalopram

A

QT prolongation and torsades de pointes

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5
Q

ECT

A

Retrograde amnesia

Cardiac arrhythmia short term

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6
Q

Monitored in SNRI

A

BP

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7
Q

Avoid with triptins

A

SSRI

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8
Q

Steroid

A 
Psychosis
Avascular necrosis
Proximal myopathy
Osteonecrosis
Hyperglycaemia
Osteoporosis
Cushings
Insomnia
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9
Q

Amiodarone

A

Lower zone fibrosis

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10
Q

Methotrexate

A

Pneumonitis

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11
Q

Beclometasone

A

Oral candidiasis

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12
Q

Azithromycin

A

Prolong QT

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13
Q

Thiazides

A 
Worsens glucose tolerance
Gout
Erectile dysfunction
Hyponatraemia
Hypokalaemia
Hypercalcaemia
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14
Q

Loop diuretic

A

Ototoxicity

Hyperkalaemia

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15
Q

Macrolides

A

Torsades de pointes

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16
Q

Reverse dabigatran

A

Idarvuzub

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17
Q

Sotalol

A

Long QT syndrome

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18
Q

Fondaparinux mechanism

A

Activates prothrombin III

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19
Q

ACEI

A

Hyperkalaemia
Cough
Angioedema

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20
Q

Beta blocker

A

Cold peripheries
Erectile dysfunction
Sleep disturbance

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21
Q

Amiodarone

A

Grey skin

Thrombophlebitis - give in central line

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22
Q

Adenosine

A

Flushing

Chest pain

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23
Q

When stop statin

A

If start macrolide]

Pregnancy

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24
Q

Never take verapamil with

A

Beta blocker

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25
Q

Ivabradine

A

Visual disturbance

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26
Q

Monitoring before amiodarone

A

Xray, LFT, TFT, UandE

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27
Q

Stop warfarin how long before surgery

A

5d

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28
Q

Bleeding times in warfarin

A

Increased PT

Normal APTT

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29
Q

What increase in creatinine after starting ACEI is acceptable

A

Up to 30%

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30
Q

Statin monitoring

A

Baseline LFT, 3m and 12m

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31
Q

ACEI contraindicated

A

Aortic stenosis

HOCM

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32
Q

Licensed CCB in HF

A

Only amlodipine

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33
Q

Nicorandil

A

Ulceration GI tract

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34
Q

Before starting sumubitril-vulsartan

A

ACEI/ARB washout

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35
Q

Lamotrigine

A

Steven Johnsone syndrome

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36
Q

Drug precipitate myasthenia crises

A

Beta blocker

37
Q

Ondensetron mechanism

A

5HT3 antagonist

38
Q

Triptin

A

Tightness of throat and chest

39
Q

Tetracycline

A

Idiopathic intracranial hypertension
Stop in pregnancy
Black hairy tongue

40
Q

Phenytoin

A

Megaloblastic anaemia
Peripheral neuropathy
Dupuytrens contracture
Folic acid deficiency

41
Q

Carbamazepine

A

Steven Johnson syndrome

42
Q

Triptin contraindicated

A

CVD

43
Q

Sodium valproate

A

Weight gain

Pancreatitis

44
Q

Chemotherapy

A

Avascular necrosis

Gout

45
Q

Bisphosphonates

A

Oesophageal problems

46
Q

Alondrenate

A

Atypical stress fracture

47
Q

TNF alpha inhibitor

A

Reactivate TB

48
Q

Methotrexate

A

Mucositis

Pneumonitis

49
Q

Sulfasalazine contra

A

Co-trimoxazole

Aspirin allergy

50
Q

Hydroxychloroquine

A

Retinopathy

51
Q

Azithioprine and pregnancy

A

Okay in pregnancy unlike others

52
Q

Colchinne

A

Diarrhoea

53
Q

Sulfazalazine

A

Decreased sperm count

54
Q

Check before starting azithioprine

A

Thiopurine methyltransferase

55
Q

Suxamethonium

A

Fasciculations
Malignant hyperthermia
Hyperkalaemia

56
Q

Etomidate

A

Adrenal suppresion

57
Q

Halothene

A

Hepatotoxicity

58
Q

Contraindication suxamethonium

A

Eye injury

59
Q

Trimethoprim

A

Hyperkalaemia

60
Q

Vancomycin

A

Red man syndrome infusing too fast

61
Q

Dapaglifozin

A

Necrotissing fascittis

62
Q

Doxycycline

A

Photosensitivity

63
Q

Antibiotic worst with alcohol

A

Metronidazole

64
Q

Metoclopramide

A

Parkinsonism

Galactorhoea

65
Q

Contraindications metoclopramide

A

PD

Bowel obstruction

66
Q

Aminosalicylate

A

Agranulocytosis

Acute pancreatitis

67
Q

PPI

A

C Diff
Osteoporosis
Decreased Mg

68
Q

Sulfasalazine blood film

A

Heinz bodies

69
Q

Tamoxifen

A

Endometrial cancer

Hot flushes

70
Q

Anastrozole

A

Osteoporosis

71
Q

Progesterone

A

Breast cancer

Irregular bleeding

72
Q

Oxybutylin

A

Fall in elderly

73
Q

Beta blocker contraindication

A

Asthma

Heart block

74
Q

Reverse magnesium sulphate

A

Calcium gluconate

75
Q

Aspirin contraindication

A

Breastfeeding

Children

76
Q

Spironolactone

A

Gynaemocastia

Hyperkalaemia

77
Q

Use instead of spironolactone

A

Eplerenone

78
Q

NSAID

A

Acute interstitial nephritis

79
Q

Lithium

A

Nephrogenic diabetes insupidus

80
Q

Statin

A

Muscle pain

Rhabdomyolysis

81
Q

Erythropoitin

A

Flu, bone pain, rash

82
Q

Chlorpromazine

A

Gynaemocastia

83
Q

Sulphonylurea

A

Weight gain

84
Q

Ferrous sulphate

A

Reduce absorption levothyroxine - take 4h apart

85
Q

Pioglitazone

A

Peripheral oedema

Cannot use in bladder cancer

86
Q

Carbimazole

A

Agranulocytosis

87
Q

Goserlin

A

Gynaemocastia

88
Q

SGLT2

A

UTI
Fourniers gangrene
Weight loss

Finals - Systems Paper (20 decks)

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