Drugs

Question 1

act mainly on the distal convoluted tubule?

Answer 1

bendroflumthiazie- thiazide diuretic

Question 2

cardio selective bbs

Answer 2

metoprolol, bisoprolol,atenolol

Question 3

non selective

Answer 3

propanolol

Question 4

clopidogrel

Answer 4

inhibits adp from binding to platelt receptors

Question 5

rivaroxaban

Answer 5

direct inhibtion of factor xa

Question 6

dabigatran

Answer 6

direct thrombin inhibitor

Question 7

increased effect of anti thrombin

Answer 7

heparin/lmwh

Question 8

inhibits vitamin k

Answer 8

warfarin

Question 9

action of calcium channel blockers

Answer 9

vasodilators

Question 10

dihydropyridines examples

Answer 10

amlodipine
nifedipine etc

Question 11

what do dihyss mainly act on

Answer 11

smooth muscle of blood vessels

Question 12

side effect of dihys

Answer 12

reflex tachy as detected by sympathetic nervous system so increases heart rate in order to maintain perfusion

Question 13

side effects of dihys

Answer 13

flushing
dizzy
peripheral oedem a
gingival hyperplasia

Question 14

nondihys examples

Answer 14

verapamil
diltiazem

Question 15

where does non dihs mainly act

Answer 15

on the heart itself

Question 16

what class are ccbs

Answer 16

class IV

Question 17

what do non dihys treat

Answer 17

tachyarrhytmias which cause increased HR

Question 18

which non dishy is more sleective

Answer 18

verapamil

Question 19

what is non dihy contraindicated in

Answer 19

bradycardia and heart failure

Question 20

what might ccbs cayse

Answer 20

brady and constipation

Question 21

can diltiazem act as a vasodilator too

Answer 21

yes

Question 22

what are non dihys mainly used for

Answer 22

chronic stable angina, hypertesion

Question 23

what are dihys mainly used for

Answer 23

hypertension as they act on the vessels

Question 24

non selective beta blockers examples

Answer 24

• Propranolol
• Timolol
• Nadolol
• Sotalol

Question 25

selective bb examples

Answer 25

Atenolol Metoprolol Bisoprolol

Question 26

where do selective bb act

Answer 26

b1

Question 27

where do non selectives act

Answer 27

b1 and 2

Question 28

whcih bb can be usedin asthma

Answer 28

selective as they dont act on b2 to bronchoconstrict

Question 29

action of locking b1

Answer 29

decreased hr and contractility

Question 30

hypertensive emergency drug

Answer 30

labetalol- non selecetive

Question 31

class I anti arrhythmic

Answer 31

sodium channel blockerscl

Question 32

class 2 anti arrhytmics

Answer 32

beta blockers

Question 33

class 3 anti arrhytmics

Answer 33

potassium channel blockers

Question 34

class iv anti arrhythmics

Answer 34

calcium channel blockers

Question 35

where do diuretics act

Answer 35

kidneys to increase production of urine to eliminate water from body

Question 36

what are thiazides secreted by

Answer 36

proximal convulated tubule

Question 37

thiazide like diiuretic example

Answer 37

indapamide

Question 38

what are longer lasting- loops or thiazides

Answer 38

thiazides

Question 39

what are most potent thiazides

Answer 39

loops

Question 40

where do loop diuretics act

Answer 40

on thick ascending loop, na,k,cl co transporter

Question 41

what are loops indictaed for

Answer 41

hyperkalaemia and hypercalcaemia

Question 42

what might short term thiazides cause

Answer 42

hyponaetraemia

Question 43

what might thiazides cause

Answer 43

hypercalcaemia and hyperglycameia

Question 44

phase 0

Answer 44

depolarisation and sodium into cell rapdily

Question 45

phase 1

Answer 45

initial repolarisation , potassium outward current

Question 46

phase 2

Answer 46

plateau phase calcium into cell

Question 47

phase 3

Answer 47

calcium channel closes, potassium still open

Question 48

phase 4

Answer 48

resting mmebrnane

Question 49

sodium channel blockers

Answer 49

slows depolarisation phase

Question 50

potassium blockers

Answer 50

slows all phases post 2 less potassium leaving cell so loger rate of repolaristion

Question 51

effects of potassium blockers

Answer 51

prolongs qt interval so may cause torsades de pointes

Question 52

example of potassium blocker

Answer 52

amiodarone