Drugs Flashcards

(8 cards)

1
Q

Propylthiouracil (PTU)

A
  1. Inhibits thyroid peroxidase → ↓ T3/T4 synthesis
  2. Also blocks peripheral T4 → T3 conversion
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2
Q

Methimazole

A

Inhibits thyroid peroxidase → ↓ T3/T4 synthesis

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3
Q

Amiodarone

A
  1. Can inhibit peripheral conversion of T4 → T3
  2. Contains iodine → may cause hypo/hyperthyroidism
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4
Q

Beta-blockers

A
  1. Inhibit T4 → T3 conversion (some types)
  2. Used in thyrotoxicosis
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5
Q

Lithium

A

Inhibits thyroid hormone release

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6
Q

Thiocyanates / Perchlorate / Nitrate / Goitrin

A

Compete with iodide uptake → inhibit hormone synthesis

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7
Q

Sulfonylureas, Glybenclamide

A

Stimulate insulin release from β-cells (block K⁺ channels)

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8
Q
A
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