Drugs Flashcards
(8 cards)
1
Q
Propylthiouracil (PTU)
A
- Inhibits thyroid peroxidase → ↓ T3/T4 synthesis
- Also blocks peripheral T4 → T3 conversion
2
Q
Methimazole
A
Inhibits thyroid peroxidase → ↓ T3/T4 synthesis
3
Q
Amiodarone
A
- Can inhibit peripheral conversion of T4 → T3
- Contains iodine → may cause hypo/hyperthyroidism
4
Q
Beta-blockers
A
- Inhibit T4 → T3 conversion (some types)
- Used in thyrotoxicosis
5
Q
Lithium
A
Inhibits thyroid hormone release
6
Q
Thiocyanates / Perchlorate / Nitrate / Goitrin
A
Compete with iodide uptake → inhibit hormone synthesis
7
Q
Sulfonylureas, Glybenclamide
A
Stimulate insulin release from β-cells (block K⁺ channels)
8
Q
A
