Drugs

Question 1

Cocaine

Answer 1

Indirect agonist, blocks reuptake channels, more monoamines in synapse

Question 2

Amphetamines

Answer 2

Bind to reuptake channels, taken up, disrupts vesicles, then reverses reuptake channels, more monoamines in synapse

Question 3

Nicotine

Answer 3

Agonist at nicotinic acetylcholine receptors, depolarisation of neurone

Question 4

Caffeine

Answer 4

Antagonist for adenosine, decreases activity of A1 and A2A receptors

Question 5

Alcohol

Answer 5

Increases inhibitory effect of GABA, inhibits excitatory effect of glutamate

Question 6

Opioids

Answer 6

Pain relief, inhibitory effect, endogenous= enkephalins and endorphins

Question 7

THC

Answer 7

Binds to cannabinoid receptors, CB1 and CB2, partial agonist

Question 8

CBD

Answer 8

Binds to cannabinoid receptor CB1, reduces some effects of THC, enhances others

Question 9

SSRIs

Answer 9

Treat depression, inhibit reuptake of serotonin, more in synapse, few weeks to work

Question 10

Ketamine

Answer 10

Antagonist at NMDA receptors, reduces activity, antidepressant and anaesthetic, thought to form new synapses in the brain

Question 11

Benzodiazepines

Answer 11

BInd at GABAA receptors, increase inhibitory activity, agonist, membrane less likely to fire action potentials