drugs

Question 1

what is pharmocology

Answer 1

the study of drugs

drugs alter biological functions

Question 2

what is the concept of dose response

Answer 2

as dose increase the response to antibiotic increases

Question 3

what does pharmacology science deal with

Answer 3

how drugs are synthesized, how drugs function, how the body handles drugs (metabolism, distribution, elimination)

Question 4

what are therapeutic drugs

Answer 4

-target symptom, invader, tissue or organ etc

Question 5

how can drugs be classified

Answer 5

• by type of chemical
• by “receptor” they act upon (membrane proteins respond to drug)
• by diseases they affect

Question 6

what are system drugs

Answer 6

cardiovascular drugs

• anti-hypertensiveness
• smooth muscle relaxants
• angiotensis converting enzyme inhibitors
• calcium channel blockers
• drugs reducing cardiac output

Question 7

what are disease drugs

Answer 7

anti-cancer agents

-cancer is many diseases, all characterized by uncontrolled cellular reproduction

Question 8

what do drugs do

Answer 8

often affect DNA
side effects
some cancers become unresponsive to drugs

Question 9

how do people search for new drugs

Answer 9

synthesis
screening natural compounds
copying bioactive molecules from humans

Question 10

what is drug testing

Answer 10

in vitro testing (in test tubes)

• biochemical
• cellular
• organs and tissues

animal testing

• toxicity
• efficacy

Question 11

how do drugs work

Answer 11

• active at cellular level
• receptor binding, activating or inhibiting cell functions
• metabolic and enzyme effects

ex. treatment of Parkinsons disease (attacks basal ganglia)

Question 12

what is Myasthenia gravis

Answer 12

droopy eye

Question 13

what is pharmacokinetics

Answer 13

science of drug distribution and duration in the body

-drugs are eliminated by metabolism and excretion

Question 14

what is cocaine pharmacology

Answer 14

• stimulant, anaesthetic, appetite suppressant
• blocker of Na+ channels (which can cause sudden cardiac death)
  postive: Euphoriant
  negatives: can cause tremors and conclusions, itching and hallucinations, insomnia and lethargy, hunger, addiction

Question 15

what are side effects of drugs

Answer 15

• all drugs have potential to cause side effects (unwanted effects)
• drug interactions are also possible (increased or decreased efficacy, synergistic effects, side effects at lower doses)