Drugs and GI tract 2 Chronic Bowel Disease (IBD) - Kahoot Quiz Flashcards

1
Q

Which drug mechanism would be most effective in treating consipation?

  • Omeprazole (PPI)
  • Ondansetron (5HT3 antagonist)
  • Senna (Myenteric Stimulant)
  • Loperamide (U-opiod agonist)
A
  • Senna
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why can’t loperamide, used to treat diarrhoea, also be used as an analgesic in palliative care?

  • It depresses the respiratory system
  • It is a u-opioid antagonist
  • It doesn’t cross the blood-brain barrier
  • It’s too addictive. It doesn’t cross the blood-brain barrier.
A
  • It doesn’t cross the blood-brain barrier
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which of the following drugs is commonly used to PREVENT travel sickness ?

  • Ondansetron
  • Hyosine
  • Famotidine
  • Metoclopramide
A

Hysosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the most crucial difference between the antiemetics, metoclopramide and domperidone?

  • Antagonism at different dopamine receptors for subtypes
  • Domperidone doesn’t cross the blood-brain barrier
  • Metoclopramide is also a 5GT3 antagonist
  • Domperidone is also a neurokinin antagonist
A
  • Domperidone doesn’t cross the blood-brain barrier
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which drug, together with antibiotics, is used to treat duodenal ulcers due to H.pylori?

  • Histamine 2 antagonist ?
  • Antacid
  • Mucosal protectant
  • Proton pump inhibator
A

PPI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which antibiotic combination would be effective in treating an H.pylori positive duodenal ulcer ?

  • Amoxicillin and Flucloxacillin
  • Clarithromycin and gentamicin
  • Clarithromycin and metronidazole
  • Amoxicillin and nitrofuanton
A
  • Clarithromycin and Metrondiazole
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which drug would be most usefull in treating the symptoms of IBS

  • Hysone hydrobromide
  • Mebeverine
  • Loperamide
  • Morphine
A

Mebeverine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which drug group might be usefull in IBS resistant to treatment with antispasmodics ?

  • Antipsychotics
  • Antiemetics
  • Antiepileptics
  • Antidepressants
A
  • Antidepressants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which GI tract is mesalazine ( 5- 5-aminosalicylic acid) the most appropriate first line of treatment?

  • IBS
  • Chrons
  • Duodenal ulcer
  • Ulcerative colitis
A

Ulcerative colitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which formulation of corticosteroid might be effective in treating ulcerative colitis ?

  • Metered dose aerosol
  • Intravitreal injection
  • Pessary
  • Rectal Foam
A
  • Rectal Foam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which drug would be most effective in the treatment of acute exacerbations of Chrons disease ?

  • Oral azathioprine
  • Oral mesalazine
  • Oral budesonide
  • intravenous ciclosporin
A
  • Intravenous ciclosporin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which drug would most effectively close the fistula associated with the more severe forms of crohns disease ?

  • Adalimumab
  • Ompeprazole
  • loperadmide
  • Mepolizumab
A

Adalimumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly