Drugs and their effect Flashcards
(26 cards)
Botulinum toxin
Blocks release of ACh
Black widow spider venom
Stimulates release of ACh
Nicotine
Stimulates nicotinic receptors
Curare
Blocks nicotinic receptor
Muscarine
Stimulates muscarinic receptors
Atropine
Blocks muscarine receptors
l-DOPA
Facilitates synthesis of DA
AMPT
Inhibits synthesis of DA
Reserpine
Inhibits storage of DA in synaptic vesicles; Inhibits storage of NE in synaptic vesicles; Inhibits storage of serotonin in synaptic vesicles
Chlorpromazine
Blocks D2 receptors
Cocaine, methylphenidate
Blocks DA reuptake
Amphetamine
Stimulates release of DA, stimulates release of NE
Deprenyl
Blocks MAO-B
MDMA
Stimulates release of NE; stimulates release of serotonin
Fluoxetine
Inhibits reuptake of serotonin
LSD
Stimulates serotonin receptors
AMPA
Stimulates AMPA receptor
Kainic acid
Stimulates kainate receptor
NMDA
Stimulates NMDA receptor
Benzodiazepines
Serve as indirect GABA AGO
Strychnine
Blocks glycine recpetors
Opiates (morphine, herion)
Stimulate opiate receptors
Naloxone
Blocks opiate receptors
Rimonabant
Blocks cannabinoid CB1 receptors