Master Drug list (effects in detail) Flashcards
(26 cards)
botulinum toxin
prevents vesicles from connecting with membrane and releasing ACh- ACh ANT
Black widow spier venom
stimulates attach and release of vesicles with Each- AGO
Nicotine
directly stimulates nicotinic ACh receptors- AGO
curare
competitive binder for nicotinic ACh receptors
muscarine
directly stimulates muscarinic ACh receptors
atropine
competitive binder for muscarinic ACh receptors
l-dopa
precursor for DA
AMPT
inactivates enzyme that turns tyrosine to l-dopa, thus is a catecholamine ANT
reserpine
stops the transport pump of monoamines into vesicles- ANT
chlorpromazine
blocks D2 receptor
cocaine, methylphenidate
blocks DA reuptake
amphetamine
blocks reuptake of DA and NE, reverses transporters so they dump NTs into cleft
deprenyl
inhibits MAO-B (which inactivates DA)- DA AGO
MDMA
stops reuptake of NE and 5HT, reverses transporters to dump them into cleft
Fluoxetine
inhibits 5HT reuptake
LSD
stimulates 5HT receptors
AMPA
stimulates AMPA glutamate recpetors
Kainic acid
simulates Kainate glutamate recpetors
NMDA
stimulates NMDA glutamate receptors
Benzodiazapines
indirect GABA AGO
Strychnine
blocks glycine receptors
opiates
stimulate opiate receptors
niloxone
blocks opiate receptors
Rimonabant
Blocks CB1 receptors for anandamide