Drugs Backwards Flashcards
Prazosin
Selective a1-antagonists
USE: HTN (not 1st), BPH
AE: Orthostatic hypotension, Reflex tachycardia
Clonidine, methyldopa
a2-agonists
USE: HTN (not 1st), methyldopa = pregnancy related HTN
AE: Sedation, Dry mouth
Aliskiren
DRIs
USE: HTN
AE: well tolerated, DONT use in pregnancy
Enalapril
ACEI
USE: HTN, HF, MI, diabetic nephropathy
AE: cough, angioedema, hyperkalemia, DONT use in pregnancy
Losartan
ARB
USE: HTN, HF, MI, diabetic nephropathy
AE: well tolerated, hyperkalemia, DONT use in pregnancy
Amlodipine
DHP CCB
USE: HTN (1st line), angina, some arr
AE: hypotension, headache, peri edema
Verapamil/Diltiazem
NON DHP CCB
USE: HTN (1st line), angina, some arr
AE: Brady, AVB, HF, constipation
Nitroglycerin
NO Donors PO
USE: angina
AE: vasodilation (hypotension, headache, flushing, reflex tachycardia)
– Tolerance: regimen must include 12-14 hr nitrate-free interval daily
Nitroprusside
NO Donors IV
USE: Hypertensive emergencies, acute HF, controlled hypotension during surgery
AE: hypotension, cyanide toxicity
Sildenafil
PDE5I
USE: ED, pulmonary HTN
AE: headache, flushing, back pain, vision loss (color), hearing loss, decrease BP if taking antihypertensive drugs
-CI if taking organic nitrates
Digoxin
Cardiac Glycoside
USE: HF, HFrEF, arr
AE: GI (N/V/D/Anorexia), arr, low therapeutic index
Dobutamine
Sympathomimetic amine
USE: acute HF (short term)
AE: tachycardia
Valsartan and sacubitril
ARNI
MOA: Increase BK
USE: HF
AE: hypotension, cough, kidney impairment
Spironolactone, Eplerenone
Aldosterone-receptor antagonist
USE: HF, HTN, edema
AE: hyperkalemia, gynecomastia
Atenolol, Propranolol
B-antagonists
(A-M selective, N-Z non)
USE: HTN (not 1st), angina, HF, MI, arr
AE: Brady, broncho-constriction, AVB, HF
-Caution in diabetics, can decrease peripheral circulation
