Drugs for influenza

Question 1

Drugs for influenza (2 groups)

Answer 1

Neuraminidase inhibitors

Adamantanes

Question 2

Neuraminidase inhibitors (2 drugs)

Answer 2

Oseltamivir

Zanamivir

Question 3

Neuraminidase inhibitors - MOA

Answer 3

Inhibits neuraminidase in influenza A and B, preventing release of virons from infected cells and preventing spread through the resp tract

Question 4

Which neuraminidase inhibitor would you prescribe to a 3 y.o with influenza?

Answer 4

I don’t even care, let that fucker die.
….
Just kidding, rescue him with Oseltamivir!

Question 5

Zanamivir - contraindications

Answer 5

Airway disease

Question 6

Adamantanes (2 drugs)

Answer 6

Amantadine

Rimantadine

Question 7

Adamantanes - MOA

Answer 7

Block M2 proton-selective ion channel, prevents acidification of influenza A, and fusion of viral membranes

Question 8

Adamantanes are not used for

Answer 8

Influenza B

Question 9

Amantadine is used for influenza A and …. because….

Answer 9

Also used for Parkinson disease because it increases the release of dopamine