Drugs of case 8

Question 1

What type of drug is Low molecular weight heparin

Answer 1

Anticoagulant

Question 2

What type of drug is Heparin

Answer 2

Anticoagulant

Question 3

What type of drug is Warfarin

Answer 3

Anticoagulant

Question 4

What type of drug is DOAC

Answer 4

Anticoagulant

Question 5

What type of drug is Ibuprofen

Answer 5

NSAID (non-steroidal anti-inflammatory drug)

Question 6

Low molecular weight heparin mechanism of action

Answer 6

Binds to Antithrombin and accelerates its inhibition of factor Xa therefore common pathway cannot occur

Question 7

Mechanism of action of heparin

Answer 7

Binds to Antithrombin III and inactivates factors IIa and Xa . It accelerates the rate of activated coagulation factors by antithrombin and prevents progression of existing clots by inhibiting further clots

Question 8

Mechanism of action of Warfarin

Answer 8

Inhibits K reductase resulting in less vitamin K. Factors II,VII,IX and X reduces prothrombin levels and this reduces the thrombogenicity of clots

Question 9

Mechanism of action of DOAC’S

Answer 9

Rivaroxaban, Apixaban and Edoxaban inhibit factor Xa and Dabigatran inhibits Thrombin

Question 10

What is the mechanism of action of ibuprofen

Answer 10

COX forms prostaglandins and thromboxane - No prostaglandins = anti-inflammatory effect. No arachidonic acid to Thromboxane A2 = no stimulation of new platelets