Drugs working on the vasculature Flashcards Preview

CV PHARM...Cardiovascular Stimulants > Drugs working on the vasculature > Flashcards

Flashcards in Drugs working on the vasculature Deck (9)
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1

Phenylephrine attributes

direct acting alpha adrenergic agonist

systemic arteriole vasoconstriction-->
--increased systolic and diastolic pressures
--REFLEXIVE decrease in HR and CO

2

Phenylephrine administration

IV, IM, SC

3

Phenylephrine use

control of hypotension, especially associated w/ regional or spinal anesthesia

4

Phenylephrine adverse effects

angina
anxiety
hallucinations/psychosis
HTN...

5

Ephedrine attributes

mixed-acting sympathomimetic
(alpha AND beta)

6

Ephedrine pk

orally active
eliminated in urine

7

Ephedrine utility

hypotension (esp. of analgesia)

8

Ephedrine effects

increases:
--HR
--CO
--variable increase in TPR

9

Ephedrine effects

angina (b/c increased work load)
ventricular dysfunction
fatal arrhythmias

herbal products containing ephedra alkaloids

Precursor of illicit amphetamine and meth!!!