(DSM) Module 14- Substance-Related And Addictive Disorders Flashcards
(29 cards)
Refers to chemical compounds that are ingested to alter mood or behavior
Substance
alters mood, behavior, or both
Psychoactive Substance
Is the ingestion of psychoactive substances in moderate amounts that does not significantly interfere with social, educational, or occupational functioning.
Substance Use
Physiological reaction to ingested substance (drunkenness, or getting high); many variables interact,
including the type of drug taken, the amount ingested, and the person’s individual biological reaction; experienced as impaired judgment, mood changes, and lowered motor ability.
Substance Intoxication
It is defined in terms of how significantly the use interferes with the user’s life which disrupts education,
job, or relationships with others, and puts one in physically dangerous situations.
Substance Use Disorder
The use of increasingly greater amounts of the drug to experience the same effect
(tolerance), and a negative physical response when the substance is no longer ingested (withdrawal)
Physiological Dependence on Drugs
Many other kinds of reinforcing experiences stimulate the release of ________, especially in the ________________, a small
subcortical area rich in dopamine
dopamine, nucleus accumbens
produces excitement, alertness, elevated mood, decreased fatigue, and sometimes increased motor activity;
directly increases activity at dopamine receptors.
Stimulants
- increases the release of dopamine from the presynaptic terminal. - reverses the dopamine transporter, causing the cell to excrete dopamine instead of reabsorbing it. - blocks certain synapses that inhibit dopamine release
Amphetamine
- blocks the reuptake of dopamine, NorE, and Serotonin, thus prolonging their effects.
Cocaine
- often prescribed for people with ADD; same mechanism as of cocaine
Methylphenidate
- a compound present in tobacco; it stimulates one type of acetylcholine receptor (nicotinic receptor) found in
CNS and nerve-muscle junction of skeletal muscles. - receptors are abundant on dopamine-releasing axon terminals in the nucleus accumbens, so it
increases dopamine in that area.
Nicotine
- major effect is to produce analgesia temporarily; include morphine, heroin and methadone, among others.
-relax people, decrease their attention-to -the-world problems, and decrease sensitivity to pain.
Opiate Drugs
- include lysergic acid diethylamide (LSD), chemically resembles serotonin. - effects include distorded sensations; alter sensory perception; produce positive psychosis
Hallucinogenic Drugs
: a cannabinoid ; relieves pain or nausea and to combat glaucoma. - psychological effects include and intensification of sensory experience and an illusion that time is passing very slowly. - cannabinoid dissolve in body’s fats and leave the body slow
Marijuana (THC)
: used for dissociative anaesthetics; produce feelings of separation from mind and body; “angel dust”
Phencyclidines
: helps people relax and may even help prevent heart attacks; damages the liver and other organs, impairs judgment, and ruin lives.
- inhibits the flow of Na across the membrane, expands the surface of membranes, decreases serotonin activity, facilitates GABA, blocks glutamate receptors, and increases
Alcohol
Substances result in behavioral sedation and can induce relaxation
Depressants
10 types of drugs for Substance-Related Disorders:
Alcohol
Opioid
Caffeine*
Sedatives, Hypnotics, or Anxiolytics
Cannabis
Stimulants
Hallucinogens
Tobacco
Inhalants
Others
Diagnostic Criteria for Substance Use Disorders (Addiction)
Impaired control
Social impairment
Risky Use
1) Using for longer periods of time than intended, or using larger amounts than intended; 2) Wanting to reduce use, yet
being unsuccessful doing so; 3) Spending excessive time getting/using/recovering from the drug use; 4) Cravings that are
so intense it is difficult to think about anything else.
Impaired control
5) People may continue to use despite problems with work, school or family/social obligations. This might include repeated
work absences, poor school performance, neglect of children, or failure to meet household responsibilities. 6) Addiction may also be indicated when someone continues substance use despite having interpersonal problems because
of the substance use. This could include arguments with family members about the substance use; or, losing important
friendships because of continued use. 7) Important and meaningful social and recreational activities may be given up or reduced because of substance use. A
person may spend less time with their family, or they may stop playing golf with their friends.
Social impairment
The key issue of this criterion is the failure to refrain from using the substance despite the harm it causes. 8) Addiction may be indicated when someone repeatedly uses substances in physically dangerous situations. For instance, using alcohol or other drugs while operating machinery or driving a car. 9) Some people continue to use addictive substances even though they are aware it is causing or worsening physical and
psychological problems. An example is the person who continues to smoke cigarettes despite having a respiratory disorder
such
Risky Use
is the body’s response to the abrupt cessation of a drug, once the body has developed a tolerance to it. The resulting cluster of symptoms is specific to each drug. Although it is very unpleasant, it does not usually require medical assistance.
Withdrawal