DVT

Question 1

Give RFs for DVT

Answer 1

Immobility
Surgery
Long haul
Pregnancy
Hormone therapy WITH oestrogen
Cancer
polycythaemia
SLE
Thrombophilia

Question 2

What thrombophilias predispose to DVT

Answer 2

Antiphospholipid syndrome
Factor V Leiden
Antithrombin deficiency
Protein C or S deficiency
Hyperhomocysteinaemia
Prothombin gene variant
Activated protein C resistance

Question 3

What is a significant finding in calf swelling?

Answer 3

> 3cm in difference of circumference

Question 4

What should be done if a doppler is negative with a positive D-dimer and Wells score suggest DVT is likely

Answer 4

Repeat USS in 6-8 days

Question 5

When should catheter directed thrombolysis be considered?

Answer 5

Symptomatic iliofemoral DVT and symptoms lasting less than 14 days

Question 6

How long should someone be on anticoagulation if there is a reversible cause?

Answer 6

3 months

Question 7

Anticoagulation length if the cause is unclear, recurrent VTE or irreversible underlying cause?

Answer 7

beyond 3 months , usually 6 months

Question 8

Anticoagulation length if active cancer?

Answer 8

3-6 months

Question 9

When are IVC filters indicated?

Answer 9

Recurrent PEs
Unsuitable for anticoagulation

Question 10

What investigations would you consider for unprovoked DVT?

Answer 10

Anti-phospholipid syndrome - check antibodies
Hereditary thrombophilias