Dyslipidemia Flashcards Preview

Endocrine- Clin Med > Dyslipidemia > Flashcards

Flashcards in Dyslipidemia Deck (20)
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1
Q

5 major types of lipoproteins

A

chylomicrons, VLDL, LDL, HDL, and IDL

2
Q

NCEP guideline for screening for high blood cholesterol

A

aged 20 or older

3
Q

lipid profile test. fast for previous…

A

9-12 hours

4
Q

USPSTF Screening recommendation for high blood cholesterol

A

begin at age 20 if increased risk of CHD. Men without increased risk begin screening at age 35. repeat every 5 years if low or average risk

5
Q

clinical manifestation if very high chylomicrons and VLDL levels

A

eruptive xanthomas

6
Q

clinical manifestation if very high levels of LDL

A

tendinous xanthomas- often on achilles or back of hand

7
Q

clinical manifestation if very high levels of triglycerides

A

lipemia retinalis

8
Q

what enzymes should be monitored when giving statins for dyslipidemia?

A

liver and muscle enzymes. because statins may cause severe, but uncommon SE including myositis, rhabdomyolysis, liver failure

9
Q

Niacin SE

A

flushing. take ASA 30 min before to avoid

10
Q

what would you warn patients of when putting them on gemfibrozil

A

SE= cholelithiasis, hepatitis, myositis

11
Q

Best med for decreaseing triglycerides

A

gemfibrozil, niacin, omega 3 acids, statsin

12
Q

inherited lipid disorders

A

familial hypercholesterolemia, familial hyperchylomicronemia

13
Q

chylomicrons

A

liporprotein that carries dietary lipid

14
Q

IDL

A

lipoprotein that carries cholesterol esters and triglycerides

15
Q

VLDL

A

lipoprotein that carries endogenous triglycerides and cholesterol

16
Q

LDL

A

lipoprotein that carries cholesterol esters

17
Q

HDL

A

lipoprotein that carries cholesterol esters

18
Q

familial hyperchylomicronemia characterized by

A

marked hypertriglyceridemia

19
Q

familial hypercholesterolemia

A

high cholesterol levels caused by unregulated synthesis of LDL

20
Q

ezetimibe

A

reduces LDL cholesterol