Thyroid Disease Flashcards
(30 cards)
2 forms of thyroid hormone
T4 (Thyroxine) and T3 (Triiodothyronine)
which thyroid hormones solely produced in thyroid gland?
T4
what is critical for thyroid hormone synthesis?
iodine
iodine deficiency during pregnancy, a/w
cretinism and inc. neonatal and infant mortality
iodine deficiency during childhood
thyroid enlargement and learning difficulties
iodine deficiency in adulthood
goiter, abnormal thyroid function
goiter most common cause worldwide
iodine deficiency, resulting in abnormal growth of thyroid gland
goiter in U.S. most common cause
multinodular goiter, chronic autoimmune thyroiditis (hashimoto’s thyroiditis), and graves disease
radioactive iodine uptake in hyperthyroidism
can be low, normal, or high
Hyperthyroidism tx
thionamides- methimazole, PTU, radioactive iodine. BB for tachycardia, tremor
what thyroid issue normal in 1st trimester
transient subclinical hyperthyroidism
hyperthyroidism in kids most commonly caused by
graves disease
thyroid dermopathy common location
pretibial myxedema- over anterior and lateral aspects of lower leg
thyroid acropachy
clubbing, seen in patients with both thyroid dermopathy and opthalmopathy
clinical manifestations in graves
hyperthyroidism, goiter, opthalmopahthy- periorbital swelling, diplopia, proptosis, scleral injection, chemosis, dermatopathy- pretibial myxedema- indurated plaques, Throid acropachy
low radioactive iodine uptake in iodine induced hyperthyroidism
iodine is still being administered
high radioactive uptake in iodine induced hyperthyroidism
sufficient time passed since last iodine uptake
goiter in hyper or hypothyroidism
both
tx and f/u with hypothyroidism
synthetic T4 is treatment. Measure TSH every 6 weeks until maintenance dose established, and yearly thereafter
most common cause of acquired hypothyroidism
chronic autoimmune thyroiditis
does hashimoto’s thyroiditis have pain associated?
no pain, no tenderness
thyroiditis a/w pain and tenderness
subacute thyroiditis, infectious thyroiditis, radiation thyroiditis, palpation or trauma induced thyroiditis
thyroiditis with no pain or tenderness
hashimotos, postpartum thyroiditis, fibrous thyroiditis, drug induced thyroiditis
hashimoto’s
autoimmune destruction of thyroid gland