Dyslipidemia

Question 1

Mevacor

Answer 1

lovastatin

me love (song that goes ah ah ah ah ah ah ahhhhh why’d you have to go ohhh away from hereeee MEH LOVE).

Question 2

Zocor

Answer 2

simvastatin

Question 3

Lescol

Answer 3

fluvastatin

Leslie gave me the flu!

Question 4

Pravachol

Answer 4

pravastatin

Question 5

Lipitor

Answer 5

atorvastatin

Question 6

Crestor

Answer 6

rosuvastatin

Question 7

Livalo

Answer 7

pitavastatin

Living a low life in the Pit. I fell in the pit, you fell in the pit. Parks and req.

Question 8

how many classes are statins divided into?

Answer 8

1. High intensity statin
2. Moderate intensity
3. Low intensity

Question 9

What are the ADRs of statins

Answer 9

Myopathy

Rhabdomyolysis

Increased liver enzymes (AST &ALT)

Small increase in risk of diabetes

Teratogenic

Question 10

How do bile acid sequestrantes work?

Answer 10

They bind bile acids in the intestine which allows for fecal excretion of cholesterol. Thus they are systemically not absorbed

Question 11

Questran

Answer 11

cholestyramine

Bile acid sequestrants
specifically a Bile acid EXCHANGE RESIN

Question 12

Colestid

Answer 12

colestipol

Bile acid sequestrants specifically bile acid EXCHANGE RESIN

Question 13

Welchol

Answer 13

cholesevelam

Bile acid sequestrants specifically an actual bile acid sequenstrant (not an exchange resin)

Question 14

bile acid sequestrants can cause what type of side effects?

Answer 14

constipation (can be indicated for diarrhea)

Stomach upset

Bloating

Flatulence

Bad taste

Question 15

What is a problem with the bile acid sequestrants besides its normal side effects?

Answer 15

the RESINS interact with many medications by binding them in the gut and inhibiting their absorption

Question 16

what is the MOA for ezetimibe (Zetia)?

Answer 16

Selective cholesterol absorption inhibitor. It inhibits cholesterol transporter in the intestinal wall (Neiman-Pick C1 like 1)

Question 17

What is a benefit of taking zeta (ezetemibe) with a statin?

Answer 17

it allows for a lower dose of statin, decreasing side effects. Data is limited though. But Zetia has limited side effects.

Question 18

Lopid

Answer 18

gemfibrozil

I got loopy after i found a gem in brazil.

Question 19

Tricor, Lofibra, Antara

Answer 19

fenofibrate

Question 20

Trilipix

Answer 20

choline fenofibrate

Question 21

Fibricor

Answer 21

fenofibric acid

Question 22

what is the best agent for increasing HDL?

Answer 22

niacin (nicotinic acid, vitamin B3)

Question 23

Niaspan

Answer 23

niacin extended release

Question 24

Slo-Niacin

Answer 24

niacin controlled release

Question 25

Niacor

Answer 25

niacin immediate release (crystalline)

Question 26

What is the main side effect with niacin? how do you block it?

Answer 26

flushing. You can block it by giving an aspirin 30 minutes before.