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PHRM 844 Module #2 > Dyslipidemia Drug Formulary > Flashcards

Dyslipidemia Drug Formulary Flashcards

1
Q

Statins

A

atorvastatin
rosuvastatin
simvastatin
pravastatin
lovastatin
pitavastatin
fluvastatin

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2
Q

Atorvastatin brand name

A

Lipitor

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3
Q

Atorvastatin dosing

A

5 mg, 10 mg, 20 mg, 40 mg, 80 mg

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4
Q

Rosuvastatin brand

A

crestor

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4
Q

Rosuvastatin dosing

A

5 mg, 10 mg, 20 mg, 40 mg

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4
Q

Atorvastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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5
Q

Rosuvastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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6
Q

Simvastatin brand

A

zocor

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7
Q

Simvastatin dosing

A

10 mg, 20 mg, 40 mg, 80 mg

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8
Q

Simvastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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9
Q

Pravastatin brand

A

pravachol

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10
Q

Pravastatin dosing

A

10 mg, 20 mg, 40 mg, 80 mg

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11
Q

Pravastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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12
Q

Lovastatin brand

A

altoprev
mevacor

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13
Q

Lovastatin dosing

A

10 mg, 20 mg, 40 mg, 80 mg

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14
Q

Lovastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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15
Q

Pitavastatin brand

A

livalo

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16
Q

Pitavastatin dosing

A

1 mg, 2 mg, 4 mg

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17
Q

Pitavastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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18
Q

Fluvastatin brand

A

lescol

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19
Q

Fluvastatin dosing

A

20 mg, 40 mg, 80 mg, XL 80 mg

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20
Q

Fluvastatin adverse effects and monitoring parameters

A

muscle toxicity: myopathy, rhabdomyolysis
watch for unusual muscle pain and darkened urine
fatigue
muscle injury: myalgias, myositis, rhabdomyolysis

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21
Q

Cholesterol absorption inhibitors

A

ezetimibe

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22
Q

Ezetimibe brand name

A

zetia

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23
Q

Ezetimibe dosing

A

10 mg

24
Q

Ezetimibe adverse effects and monitoring parameters

A

fatigue
diarrhea
GI upset

25
Q

PCSK-9 Inhibitors

A

evolocumab
alirocumab

26
Q

Evolocumab brand name

A

repatha

27
Q

Evolocumab dosing

A

140 mg every 2 weeks or 240 mg once a month

28
Q

Evolocumab adverse effects and monitoring parameters

A

GI upset
increased LFTs
injection site rxn
myalgia
influenza

29
Q

Alirocumab brand name

A

praluent

30
Q

Alirocumab dosing

A

every 2 weeks either 75 or 150 mg

31
Q

Alirocumab adverse effects and monitoring parameters

A

GI upset
increased LFTs
injection site rxn
myalgia
influenza

32
Q

Bile acid sequestrants

A

cholestyramine
colesevelam
colestipol

33
Q

Cholestyramine brand name

A

questran
prevalite

34
Q

Cholestyramine dosing

A

4 g one or two times a day; increase to 8 to 24 g a day

35
Q

Cholestyramine adverse effects and monitoring parameters

A

imparied absorption of fat-soluble vitamins (A, D, E, K)
hypernatremia
hyperchloremia
GI obstruction

36
Q

Colesevelam brand name

A

WelChol

37
Q

Colesevelam dosing

A

625 mg tab, six tabs a day

38
Q

Colesevelam adverse effects and monitoring parameters

A

imparied absorption of fat-soluble vitamins (A, D, E, K)
hypernatremia
hyperchloremia
GI obstruction

39
Q

Colestipol brand name

A

colestid

40
Q

Colestipol dosing

A

2 to 16 g

41
Q

Colestipol adverse effects and monitoring parameters

A

imparied absorption of fat-soluble vitamins (A, D, E, K)
hypernatremia
hyperchloremia
GI obstruction

42
Q

Fibrates

A

fenofibrate
gemfibrozil

43
Q

Fenofibrate brand name

A

Antara, Fenoglide, Lipofen, Lofibra, TriCor, Triglide

44
Q

Fenofibrate dosing

A

TriCor tablet: 48mg, 145mg
Lofibra tablet: 54mg, 160mg
Fenoglide tablet: 40mg, 120mg
Triglide tablet: 160mg
Lipofen capsule: 50mg, 150mg

45
Q

Fenofibrate adverse effects and monitoring parameters

A

GI disturbances, rash, myalgia, dizziness

46
Q

Gemfibrozil brand name

A

lopid

47
Q

Gemfibrozil dosing

A

600 mg tab, twice a day

48
Q

Gemfibrozil adverse effects and monitoring parameters

A

GI disturbances, rash, myalgia, dizziness

49
Q

Omega-3 Fatty Acids

A

omega-3 fatty acid
icosapent ethyl

50
Q

Others

A

niacin

51
Q

Omega-3 fatty acid brand name

A

lovaza

52
Q

Omega-3 fatty acid dosing

A

lovaza: 2-4 g daily or divided BID

53
Q

Omega-3 fatty acid adverse effects and monitoring parameters

A

bad breath, GI symptoms

54
Q

Icosapent ethyl brand name

A

vascepa

55
Q

Icosapent ethyl dosing

A

2 g BID

56
Q

Icosapent ethyl adverse effects and monitoring parameters

A

bad breath, GI symptoms

57
Q

Niacin brand name

A

niacor
niaspan
slo-niacin

58
Q

Niacin dosing

A

500-2000 mg/day

59
Q

Niacin adverse effects and monitoring parameters

A

flushing and itching, tingling of upper body, and headache

PHRM 844 Module #2 (23 decks)

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