Dyslipidemia Quiz Drug Formulary Flashcards

(66 cards)

1
Q

Atorvastatin

A

Lipitor

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2
Q

Rosuvastatin

A

Crestor

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3
Q

Simvastatin

A

Zocor

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4
Q

Pravastatin

A

Pravachol

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5
Q

Lovastatin

A

Altoprev, Mevacor

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6
Q

Pitavastatin

A

Livalo

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7
Q

Fluvastatin

A

Lescol

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8
Q

Ezetimibe

A

Zetia

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9
Q

Evolocumab

A

Repatha

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10
Q

Alirocumab

A

Praluent

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11
Q

Cholestyramine

A

Questran

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12
Q

Colsevelem

A

Welchol

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13
Q

Colestipol

A

Colestid

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14
Q

Fenofibrate

A

Tricor

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15
Q

Gemfibrozil

A

Lopid

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16
Q

Omega-3 fatty acid

A

Lovaza

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17
Q

Icosapent ethyl

A

Vascepa

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18
Q

Niacin

A

Niacor

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19
Q

Ezetimibe (Zetia) drug class

A

Cholesterol absorption inhibitor

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20
Q

Evolocumab (Repatha) & Alirocumab (Praluent) drug class

A

PCSK-9 Inhibitors

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21
Q

Cholestyramine (Questran), Colsevelem (Welchol), Colestipol (Colestid) drug class

A

Bile acid sequestrants

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22
Q

Fenofibrate (Tricor) & Gemfibrozil (Lopid) drug class

A

Fibrates

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23
Q

Omega-3 fatty acid (Lovaza) & Icosapent ethyl (Vascepa) drug class

A

Omega-3 fatty acids

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24
Q

Niacin (Niacor) drug class

A

Other (antilipemic agent)

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25
Statin side effects
headache, diarrhea, muscle pain, dark urine, sleep problems, dizziness
26
ezetimibe side effects
fatigue, diarrhea, GI upset
27
PCSK-9 Inhibitor side effects
flu like symptoms, muscle pain, injection site soreness,
28
Bile Acid Sequestrant side effects
constipation, stomach pain, heartburn, loss of appetite, indigestion
29
fibrate side effects
abdominal pain, nausea, back pain, skin rash, jaundice
30
omega-3 fatty acid side effects
diarrhea, abdominal pain, nausea, eructation (burping), bad taste (dysgeusia)
31
Niacin side effects
flushing, diarrhea, cough, fatigue, abdominal pain
32
statin contraindications
pregnancy, lactation, liver failure/cirrhosis
33
cholesterol absorption inhibitors (ezetimibe) contraindications
pregnancy, lactation, liver disease, elevated serum transaminase
34
PCSK-9 inhibitor contraindications
hypersensitivity, latex (repatha packaging)
35
Bile acid sequestrant contraindications
complete biliary obstruction, gastroparesis, at risk for bowel obstruction, renal impairment
36
fibrate contraindications
liver disease, biliary cirrhosis, kidney disease, gallbladder disease, pregnancy, breast feeding
37
Omega-3 fatty acid contraindications
diabetes, a fib, liver, thyroid, pancreatic disease
38
Niacin (Niacor) contraindications
hepatic disease, elevations in hepatic transaminases, active peptic ulcer, arterial hemorrhage, pregnancy and lactation
39
Statin monitoring parameters
check lipid panel at baseline, 6-8 weeks after stating, then every 4-6 months. Check LFTs at baseline, after 12 weeks, then annually
40
Ezetimibe monitoring parameters
liver function tests
41
PCSK-9 inhibitors monitoring parameters
LDL levels
42
Bile acid sequestrant monitoring parameters
Triaglycerides
43
Fibrates monitoring parameters
none unless concomitant disease (renal, serum transaminases, gallbladder, PT/INR)
44
Omega-3 fatty acid monitoring parameters
LDL levels, AST, ALT in patients with hepatic impairment
45
Niacin monitoring parameters
blood sugar in diabetes patients, phosphorus levels for pts at risk for hypophosphatemia
46
Low intensity statins
simvastatin 10 mg, pravastatin 10-20 mg, lovastatin 20 mg, fluvastatin 20-40 mg
47
Moderate intensity statins
atorvastatin 10-20 mg, rosuvastatin 5-10 mg, simvastatin 20-40 mg, pravastatin 40-80 mg, lovastatin 40-80 mg, fluvastatin 40 mg BID, fluvastatin XL 80 mg, pitavastatin 1-4 mg
48
High intensity statins
atorvastatin 40-80 mg, rosuvastatin 20-40 mg
49
Atorvastatin dosing
Moderate intensity: 10-20 mg High intensity: 40-80 mg
50
Rosuvastatin dosing
moderate intensity: 5-10 mg high-intensity: 20-40 mg
51
Simvastatin dosing
low intensity: 10 mg moderate intensity: 20-40 mg
52
Pravastatin dosing
low intensity: 10-20 mg moderare intensity: 40-80 mg
53
lovastatin dosing
low intensity: 20 mg moderate intensity: 40-80 mg
54
pitavastatin dosing
moderate intensity: 1-4 mg
55
fluvastatin dosing
low intensity: 20-40 mg moderate intensity: 40 mg BID or XL 80 mg
56
ezetimibe dosing
10 mg
57
evolocumab dosing
140 mg every 2 weeks or 420 mg monthly
58
alirocumab dosing
75 mg every 2 weeks or 300 mg monthly
59
cholestyramine dosing
4-16 g
60
colsevelam dosing
3.75 g
61
colestipol dosing
5-30 g
62
fenofibrate dosing
40-160 mg
63
gemfibrozil dosing
600 mg BID
64
omega-3 fatty acid dosing
2 g BID or 4 g QD
65
icosapent ethyl dosing
2 g BID
66
niacin dosing
initial 200 mg - max 6 g / day (3 doses)